Impact of cytosine methylation on DNA binding specificities of human transcription factors
… the effect of cytosine methylation on transcription factor binding… transcription factors and
extended DNA binding domains to unmethylated and CpG-methylated DNA by using methylation…
extended DNA binding domains to unmethylated and CpG-methylated DNA by using methylation…
Effects of cytosine methylation on transcription factor binding sites
… methylation in promoters is closely linked to downstream gene repression. However, whether
DNA methylation … , then DNA methylation may affect the affinity of transcription factors (TFs) …
DNA methylation … , then DNA methylation may affect the affinity of transcription factors (TFs) …
The effects of cytosine methylation on general transcription factors
… methylation effects on DNA/protein interactions, we have chosen three human transcription
factors … estrogen receptor (ER) with methylated or unmethylated DNA binding sequences, …
factors … estrogen receptor (ER) with methylated or unmethylated DNA binding sequences, …
Cytosine methylation does not affect binding of transcription factor Sp1.
MA Harrington, PA Jones… - Proceedings of the …, 1988 - National Acad Sciences
… investigate the effect of cytosine methylation on the binding of the transcription factor Spl to
… The results therefore preclude a direct effect of cytosine methylation on Spl-DNA interactions…
… The results therefore preclude a direct effect of cytosine methylation on Spl-DNA interactions…
Toward a base-resolution panorama of the in vivo impact of cytosine methylation on transcription factor binding
A Hernandez-Corchado, HS Najafabadi - Genome Biology, 2022 - Springer
… Transcription factors (TFs) are key regulators of gene expression. Each TF usually … , among
which cytosine methylation is traditionally viewed as having a repressive effect on TF binding […
which cytosine methylation is traditionally viewed as having a repressive effect on TF binding […
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter.
F Watt, PL Molloy - Genes & development, 1988 - genesdev.cshlp.org
… examined whether methylation of CpG dinucleotides located within the binding site for a
specific transcription factor, MLTF or USF, affects its binding to DNA. This HeLa cell factor binds …
specific transcription factor, MLTF or USF, affects its binding to DNA. This HeLa cell factor binds …
Cytosine methylation of mitochondrial DNA at CpG sequences impacts transcription factor A DNA binding and transcription
V Dostal, MEA Churchill - Biochimica et Biophysica Acta (BBA)-Gene …, 2019 - Elsevier
… In this study we examined the effects of cytosine methylation of CpG on TFAM DNA binding,
TFAM-dependent DNA compaction and transcription. Quantitative binding experiments …
TFAM-dependent DNA compaction and transcription. Quantitative binding experiments …
Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes
… effect of cytosine methylation on binding affinity, we developed a feature-based generalized
linear model to estimate the change in binding free energy associated with cytosine …
linear model to estimate the change in binding free energy associated with cytosine …
Sensitivity of transcription factors to DNA methylation
… While the chemical evidence of cytosine methylation was initially discovered in 1948 [16],
the first functional evidence that it could regulate physiological processes emerged in 1975 [17]…
the first functional evidence that it could regulate physiological processes emerged in 1975 [17]…
[HTML][HTML] Toward a mechanistic understanding of DNA methylation readout by transcription factors
… This review will primarily cover in vitro–based methods that quantify how TFs respond to
cytosine methylation and address to what extent the results of these assays have improved the …
cytosine methylation and address to what extent the results of these assays have improved the …
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- mitochondrial transcription factor
- dna methylation transcription factor occupancy
- human transcription factors
- cytosine methylation general transcription factors
- methylation patterns transcription factor bindings
- dna methylation states transcription factors
- transcription factor widespread effects
- transcription factor dna methylation profiles
- transcription factor quantitative effects
- transcription factor dna methylation patterns
- transcription factor deoxycytidine methylation
- specific transcription factors
- transcription factor complexes
- sp1 and sp3 transcription factor sp4
- cytosine methylation base resolution
- transcription factor binding regions