Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma

F Liu‐Smith, FL Meyskens - Molecular nutrition & food research, 2016 - Wiley Online Library
… of flavonoids on melanin synthesis. The current understanding of melanin synthesis follows
… which MITF serves as the master transcriptional factor activating tyrosinase, DCT and TYRP-1…

[HTML][HTML] Sarsasapogenin increases melanin synthesis via induction of tyrosinase and microphthalmia-associated transcription factor expression in melan-a cells

E Moon, AJ Kim, SY Kim - Biomolecules & therapeutics, 2012 - ncbi.nlm.nih.gov
… In this study, SAR significantly induced melanin synthesis in murine melanocytes melan-a
cells. Although SAR did not influence melanogenic enzyme activity, the protein expressions of …

… alpha-melanocyte stimulating hormone-induced melanin synthesis through suppressing transactivation activity of microphthalmia-associated transcription factor

JY Lee, HJ Choi, TW Chung, CH Kim… - Journal of Natural …, 2013 - ACS Publications
… reduced α-MSH-stimulated melanin synthesis by suppressing … transcription factor (MITF)
as a key transcription factor for … melanin synthesis and function of MITF transcription factor. …

Fifteen‐year quest for microphthalmia‐associated transcription factor target genes

Y Cheli, M Ohanna, R Ballotti… - Pigment cell & …, 2010 - Wiley Online Library
… control of TYROSINASE, TYRP1 and DCT genes, encoding the three enzymes involved in
melanin synthesis or melanogenesis. Sixteen years after the first description of MITF, more …

Transcription physiology” of pigment formation in melanocytes: central role of MITF

J Vachtenheim, J Borovanský - Experimental dermatology, 2010 - Wiley Online Library
… The polymeric compound melanin is synthesized within melanocytes in the … for melanin
synthesis and deposition are coordinately expressed in melanocytes. The transcription factor

Transcription factor AacmrA mediated melanin synthesis regulates the growth, appressorium formation, stress response and pathogenicity of pear fungal Alternaria …

R Li, Y Li, W Xu, M Zhang, Q Jiang, Y Liu, L Li, Y Bi… - Fungal Biology, 2022 - Elsevier
… to explore various functions of melanin synthesis transcription factor AacmrA. We discussed
the regulation of AacmrA on the synthesis of A. alternata melanin, clarified the effect of …

The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis

F Vetrini, A Auricchio, J Du, B Angeletti… - … and cellular biology, 2004 - Am Soc Microbiol
melanin synthesis or melanosome biogenesis. Here we show that a common transcriptional
… Tissue-specific control of Oa1 transcription lies within a region of 617 bp that contains the E-…

Heat Shock Transcription Factor CgHSF1 Is Required for Melanin Biosynthesis, Appressorium Formation, and Pathogenicity in Colletotrichum gloeosporioides

X Gao, Q Wang, Q Feng, B Zhang, C He, H Luo, B An - Journal of Fungi, 2022 - mdpi.com
… , and severe defects in melanin biosynthesis. Moreover, four melanin synthetic genes were
… in fungal pathogenicity via the transcriptional activation of melanin biosynthesis. Our study …

Transcription Factor Amr1 Induces Melanin Biosynthesis and Suppresses Virulence in Alternaria brassicicola

Y Cho, A Srivastava, RA Ohm, CB Lawrence… - PLoS …, 2012 - journals.plos.org
… Here, we report on another transcription factor gene, Amr1, which negatively regulates a …
a transcription factor in this study, Amr1, which regulates the melanin synthesis pathway in A…

Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici

P Zhang, S Zhou, G Wang, Z An, X Liu… - Molecular …, 2019 - Wiley Online Library
… results in different strains, we hypothesize that PfmaH is the key regulator controlling DHN
melanin synthesis of spores while PfmaF stimulates PfmaH in promoting melanin synthesis. …