Series introduction: the transcription factor NF-κB and human disease

AS Baldwin - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… through the present, the transcription factor NF-κB has attracted widespread interest based
on its … Importantly, and consistent with the last point, NF-κB has been shown to be the target of …

Nuclear transcription factor NF-kappa B: role in biology and medicine

BB Aggarwal, Y Takada, S Shishodia, AM Gutierrez… - 2004 - nopr.niscpr.res.in
… Beginning with its discovery in 1986 and continuing through the present, transcription
factor NF-KB has attracted widespread interest based on its unusual regulation, the variety of …

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

QW Xie, Y Kashiwabara, C Nathan - Journal of Biological Chemistry, 1994 - ASBMB
… Thus, activation of NF-KB/Rel is critical in the induction of iNOS by LPS. However,
additional, newly synthesized proteins contribute to the NF-KBd-dependent transcription factor

Transcription factor NF-κB: an update on intervention strategies

A Panday, ME Inda, P Bagam, MK Sahoo… - Archivum immunologiae …, 2016 - Springer
… ) also regulate NF-κB activation. Based on the involvement of transcription factor NF-κB in
diverse … , activity, and the transcriptional potential. In this review, we will highlight the role of …

The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits.

S Grimm, PA Baeuerle - Biochemical journal, 1993 - ncbi.nlm.nih.gov
… and structural aspects of NF-KB subunits. NF-KB is a transcription factor that is activated in
many … , stress factors) or secondary pathogenic stimuli (inflammatory cytokines). The active …

The transcription factor NF-κB and the regulation of vascular cell function

R De Martin, M Hoeth, R Hofer-Warbinek… - … , and vascular biology, 2000 - Am Heart Assoc
… of the nuclear factor (NF)-κB family of transcription factors. The … The beneficial and usually
transient NF-κB–dependent gene … on the favorable and adverse roles of NF-κB in the context of …

[HTML][HTML] Transcription factor-κB (NF-κB) and renal disease

C Guijarro, J Egido - Kidney international, 2001 - Elsevier
NF-κB dimers do not promote gene transcription by themselves, … , NF-κB interacts with a
variety of other transcription factors in … factors most commonly involved in the activation of NF-κB

IκB: a specific inhibitor of the NF-κB transcription factor

PA Baeuerle, D Baltimore - Science, 1988 - science.org
… synthesis, suggesting that NF-KB is present in most cell types as an inactive precursor before
TPA stimulation. We showed earlier that the NF-KB transcription factor can be detected in …

The NF-κB family of transcription factors and its regulation

A Oeckinghaus, S Ghosh - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
factor-κB (NF-κB) consists of a family of transcription factors that … Inducible NF-κB activation
depends on phosphorylation-… of NF-κB proteins (IκBs), which retain inactive NF-κB dimers in …

Transcription factor NF-κB as a potential biomarker for oxidative stress

R Van den Berg, G Haenen, H Van den Berg… - British Journal of …, 2001 - cambridge.org
… of transcription factors, such as of the transcription factor NF-kB (nuclear factor-kB), in the
pathogenesis of various diseases. NFkB is involved in the control of the transcription of a …