Establishing nucleosome architecture and stability at promoters: Roles of pioneer transcription factors and the RSC chromatin remodeler

S Kubik, MJ Bruzzone, D Shore - Bioessays, 2017 - Wiley Online Library
nucleosome forms immediately upstream of the transcription … This “fragile” nucleosome (FN)
promoter architecture relies … ) nucleosome remodeler and pioneer transcription factors (PTFs)…

[HTML][HTML] A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription

H van Bakel, K Tsui, M Gebbia, S Mnaimneh… - PLoS …, 2013 - journals.plos.org
… Our parallel expression profiling compendium revealed extensive transcriptionnucleosome
occupancy and positioning. We show that the nucleosome-excluding transcription factors

Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH

J Vierstra, H Wang, S John, R Sandstrom… - Nature …, 2014 - nature.com
… minor groove of DNA on the nucleosome surface, resulting in … exposition of regulatory DNA
architecture that exploits the full … , TF-nucleosome interactions and nucleosome architecture

The nucleosome: a powerful regulator of transcription

AP Wolffe, H Kurumizaka - Progress in nucleic acid research and molecular …, 1998 - Elsevier
transcription factor access to nucleosomal DNA and relieves inhibitory effects on transcriptional
… the coevolution of DNA with both the architectural proteins that package the double helix …

Architecture of the SWI/SNF-nucleosome complex

ML Dechassa, B Zhang… - … and cellular biology, 2008 - Am Soc Microbiol
nucleosomes two helical turns from the dyad axis and that the Snf6 subunit is proximal to
the transcription factor … the histone octamer and not with nucleosomal DNA. The model of the …

[HTML][HTML] Structural insights into the interaction between transcription factors and the nucleosome

E Morgunova, J Taipale - Current Opinion in Structural Biology, 2021 - Elsevier
transcription factornucleosome interactions. These include in vitro methods such as
nucleosome … interaction landscape between transcription factors and the nucleosome is very rich …

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

AN Schep, JD Buenrostro, SK Denny… - Genome …, 2015 - genome.cshlp.org
… Examining the distance to the nearest nucleosome for other sequence-specific transcription
factors, we see that CTCF appears unique in its ability to strongly position flanking …

[HTML][HTML] Nucleosome architecture throughout the cell cycle

Ö Deniz, O Flores, M Aldea, M Soler-López… - Scientific reports, 2016 - nature.com
… cell cycle plasticity of nucleosome architecture around key regions: transcription start/…
nucleosome rearrangements and cell cycle-related dynamics in DNA replication and transcription

[HTML][HTML] Design of synthetic yeast promoters via tuning of nucleosome architecture

KA Curran, NC Crook, AS Karim, A Gupta… - Nature …, 2014 - nature.com
… Specifically, we utilized common glycolytic transcription factor binding sites embedded in
random spacer sequences as the lead designs for our algorithm (Fig. 7a, Supplementary Table …

[HTML][HTML] Regulation of nucleosome architecture and factor binding revealed by nuclease footprinting of the ESC genome

SJ Hainer, TG Fazzio - Cell reports, 2015 - cell.com
… To test the roles of these complexes in regulation of transcription factor and chromatin
regulatory factor binding, we focused on the information provided by the small reads (≤80 bp) …