Establishing nucleosome architecture and stability at promoters: Roles of pioneer transcription factors and the RSC chromatin remodeler
… nucleosome forms immediately upstream of the transcription … This “fragile” nucleosome (FN)
promoter architecture relies … ) nucleosome remodeler and pioneer transcription factors (PTFs)…
promoter architecture relies … ) nucleosome remodeler and pioneer transcription factors (PTFs)…
[HTML][HTML] A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription
H van Bakel, K Tsui, M Gebbia, S Mnaimneh… - PLoS …, 2013 - journals.plos.org
… Our parallel expression profiling compendium revealed extensive transcription … nucleosome
occupancy and positioning. We show that the nucleosome-excluding transcription factors …
occupancy and positioning. We show that the nucleosome-excluding transcription factors …
Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH
J Vierstra, H Wang, S John, R Sandstrom… - Nature …, 2014 - nature.com
… minor groove of DNA on the nucleosome surface, resulting in … exposition of regulatory DNA
architecture that exploits the full … , TF-nucleosome interactions and nucleosome architecture …
architecture that exploits the full … , TF-nucleosome interactions and nucleosome architecture …
The nucleosome: a powerful regulator of transcription
AP Wolffe, H Kurumizaka - Progress in nucleic acid research and molecular …, 1998 - Elsevier
… transcription factor access to nucleosomal DNA and relieves inhibitory effects on transcriptional
… the coevolution of DNA with both the architectural proteins that package the double helix …
… the coevolution of DNA with both the architectural proteins that package the double helix …
Architecture of the SWI/SNF-nucleosome complex
ML Dechassa, B Zhang… - … and cellular biology, 2008 - Am Soc Microbiol
… nucleosomes two helical turns from the dyad axis and that the Snf6 subunit is proximal to
the transcription factor … the histone octamer and not with nucleosomal DNA. The model of the …
the transcription factor … the histone octamer and not with nucleosomal DNA. The model of the …
[HTML][HTML] Structural insights into the interaction between transcription factors and the nucleosome
E Morgunova, J Taipale - Current Opinion in Structural Biology, 2021 - Elsevier
… transcription factor — nucleosome interactions. These include in vitro methods such as
nucleosome … interaction landscape between transcription factors and the nucleosome is very rich …
nucleosome … interaction landscape between transcription factors and the nucleosome is very rich …
Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions
… Examining the distance to the nearest nucleosome for other sequence-specific transcription
factors, we see that CTCF appears unique in its ability to strongly position flanking …
factors, we see that CTCF appears unique in its ability to strongly position flanking …
[HTML][HTML] Nucleosome architecture throughout the cell cycle
… cell cycle plasticity of nucleosome architecture around key regions: transcription start/…
nucleosome rearrangements and cell cycle-related dynamics in DNA replication and transcription…
nucleosome rearrangements and cell cycle-related dynamics in DNA replication and transcription…
[HTML][HTML] Design of synthetic yeast promoters via tuning of nucleosome architecture
… Specifically, we utilized common glycolytic transcription factor binding sites embedded in
random spacer sequences as the lead designs for our algorithm (Fig. 7a, Supplementary Table …
random spacer sequences as the lead designs for our algorithm (Fig. 7a, Supplementary Table …
[HTML][HTML] Regulation of nucleosome architecture and factor binding revealed by nuclease footprinting of the ESC genome
SJ Hainer, TG Fazzio - Cell reports, 2015 - cell.com
… To test the roles of these complexes in regulation of transcription factor and chromatin
regulatory factor binding, we focused on the information provided by the small reads (≤80 bp) …
regulatory factor binding, we focused on the information provided by the small reads (≤80 bp) …
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