Competition between DNA methylation and transcription factors determines binding of NRF1

S Domcke, AF Bardet, P Adrian Ginno, D Hartl… - Nature, 2015 - nature.com
… contribution of DNA methylation to constrained TF binding, we mapped DNase-I-hypersensitive
sites in murine stem cells in the presence and absence of DNA methylation. Methylation-…

[HTML][HTML] Toward a mechanistic understanding of DNA methylation readout by transcription factors

JF Kribelbauer, XJ Lu, R Rohs, RS Mann… - Journal of molecular …, 2020 - Elsevier
… was observed, namely that DNA methylation can actively block the binding of the
transcription factor NRF1 [17], again underscoring that DNA methylation can have a biologically …

[HTML][HTML] Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation

S Kaluscha, S Domcke, C Wirbelauer, MB Stadler… - Nature …, 2022 - nature.com
… Taken together, our findings provide insights into transcriptional repression through DNA
methylation of CpG-rich regulatory regions that drive genes and repeats, and favor a model of …

[HTML][HTML] Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions

A Feldmann, R Ivanek, R Murr, D Gaidatzis… - PLoS …, 2013 - journals.plos.org
… actual occupancy of DNA-binding factors is linked to DNA methylation at the level … DNA
methylation within the CTCF motif. In line with a dynamic model of binding and DNA methylation

[HTML][HTML] The dynamic changes of DNA methylation and histone modifications of salt responsive transcription factor genes in soybean

Y Song, D Ji, S Li, P Wang, Q Li, F Xiang - PloS one, 2012 - journals.plos.org
… of three of the four DNA methylated transcription factors was correlated with an increased …
a critical role for some transcription factors' activation/repression by DNA methylation and/or …

[HTML][HTML] DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity

R Roy, S Ramamoorthy, BD Shapiro, M Kaileh… - Immunity, 2021 - cell.com
… To identify immune-cell-specific patterns of DNA methylation, we fractionated human blood
into 11 subsets using a combination of magnetic beads and flow cytometry (Figures 1A and …

Dnmt1/transcription factor interactions: an alternative mechanism of DNA methylation inheritance

E Hervouet, FM Vallette, PF Cartron - Genes & cancer, 2010 - journals.sagepub.com
DNA methylation inheritance without site preference. We also show that the Dnmt1-PCNA-UHRF1
and Dnmt1/transcription factor complexes methylate DNA … existing methylation pattern …

[HTML][HTML] DNMTs and impact of CpG content, transcription factors, consensus motifs, lncRNAs, and histone marks on DNA methylation

J Loaeza-Loaeza, AS Beltran, D Hernández-Sotelo - Genes, 2020 - mdpi.com
factors (TF) binding sites, lncRNAs, and histone marks to regulate DNA methylation. We also
review how complexes of DNMTs/TFs or DNMTs/lncRNAs are involved in DNA methylation

Increased DNA methylation and reduced expression of transcription factors in human osteoarthritis cartilage

O Alvarez‐Garcia, KM Fisch… - Arthritis & …, 2016 - Wiley Online Library
… , we identified several transcription factors that are differentially methylated and repressed
in … modulation of DNA methylation is able to regulate transcription of these factors in cultured …

General Transcription Factor Binding at CpG Islands in Normal Cells Correlates with Resistance to De novo DNA Methylation in Cancer Cells

C Gebhard, C Benner, M Ehrich, L Schwarzfischer… - Cancer research, 2010 - AACR
… comparative DNA methylation profiles of … DNA methylation states, we discovered several
nonredundant sequences in CpG islands that were resistant to aberrant de novo methylation in …