Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites
… where DNA methylation associates with cell identity. Here we show that DNA methylation …
-to-macrophage differentiation occur at transcription factor binding sites, and, in contrast to …
-to-macrophage differentiation occur at transcription factor binding sites, and, in contrast to …
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels
… transcription factor binding as well as transcription factor abundance are associated with
changes in DNA methylation near transcription factor … the regulation of DNA methylation in the …
changes in DNA methylation near transcription factor … the regulation of DNA methylation in the …
Detecting and interpreting DNA methylation marks
… regulation of gene expression by methylation’ [30]. Indeed, the recognition of some
sequence-specific transcription factors is blocked by cytosine methylation only within the context of a …
sequence-specific transcription factors is blocked by cytosine methylation only within the context of a …
Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins
CA Kemme, R Marquez, RH Luu… - Nucleic acids …, 2017 - academic.oup.com
… that sequester transcription factors. … transcription factor Egr-1 with its targets. In this study,
using a stopped-flow fluorescence method, we examined the kinetic impact of DNA methylation …
using a stopped-flow fluorescence method, we examined the kinetic impact of DNA methylation …
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
J Boyes, A Bird - Cell, 1991 - cell.com
… with the binding of transcription factors, we would have expected some inhibition to … of DNA
methylation on transcription of these three promoters. In the case of PCMVjun, transcription …
methylation on transcription of these three promoters. In the case of PCMVjun, transcription …
CpG methylation recruits sequence specific transcription factors essential for tissue specific gene expression
R Chatterjee, C Vinson - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
… present understanding of DNA methylation in normal cells … , although other cytosine
methylation is observed in the … DNA methylation, the genomic distribution of CG methylation, and …
methylation is observed in the … DNA methylation, the genomic distribution of CG methylation, and …
DNA methylation: roles in mammalian development
ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… locus induced appreciable local demethylation, confirming the dominance of transcription
factor binding over DNA methylation in this context 12 . Short, cis-acting sequences are often …
factor binding over DNA methylation in this context 12 . Short, cis-acting sequences are often …
Impacts of pretranscriptional DNA methylation, transcriptional transcription factor, and posttranscriptional microRNA regulations on protein evolutionary rate
TJ Chuang, TW Chiang - Genome biology and evolution, 2014 - academic.oup.com
… In this way, we show that the levels of DNA methylation of … factors are controlled. Interestingly,
protein evolutionary rates are positively correlated with the level of promoter methylation, …
protein evolutionary rates are positively correlated with the level of promoter methylation, …
Human telomerase reverse transcriptase regulation by DNA methylation, transcription factor binding and alternative splicing
BA Avin, CB Umbricht… - … journal of oncology, 2016 - spandidos-publications.com
… transcribed genes, since methylated DNA is associated with gene silencing through both
interference of transcription factor … Importantly, aberrant DNA methylation is a hallmark of …
interference of transcription factor … Importantly, aberrant DNA methylation is a hallmark of …
SNPs in sites for DNA methylation, transcription factor binding, and miRNA targets leading to allele-specific gene expression and contributing to complex disease risk …
… For SNPs interacting with DNA methylation, we identified 533 and 9,862 entries from … for
SNPs interacting with DNA methylation, and 11 articles for SNPs in miRNA binding sites (Fig. 2). …
SNPs interacting with DNA methylation, and 11 articles for SNPs in miRNA binding sites (Fig. 2). …