… We conclude that Sen1 levels are carefully regulated to prevent aberrant termination. We
suggest that ncRNA levels and coding gene transcription termination are modulated by Sen1 …

… The Nrd1-Nab3-Sen1 (NNS) complex carries out the transcription termination of non-coding …
Here we have identified three sequence motifs in Sen1 that mediate direct interactions with …

… transcription-coupled processes. Here we describe an in vitro transcription-termination …
for the analysis of the mechanism of termination by the yeast helicase Sen1. In this system, we …

… In addition, we find that dissociation of the EC by Sen1 is … of Sen1-dependent transcription
termination and a rationale for the kinetic competition between elongation and termination. …

… The earlier structure of Pcf11 CID [52,53], a CFI complex component [54,55], and the Rtt103
CID structure [56], a Rat1 exonuclease associated transcription termination factor [57], share …

… with Pol II complex during factor-dependent termination. Our results … of Sen1 and a critical
interaction between Sen1 and Pol II complex for factor-dependent transcription termination in …

… in the absence of Sen1 requires both the lack of interaction with the replisome and the
transcription termination defects at non-coding RNA genes. We show that Sen1 also functions at …

… for the role of Sen1 NIM in non‐coding transcription termination, we performed RNAseq
transcriptome analyses of ∆rrp6 strains expressing either the wt or the ∆NIM version of Sen1. As …

… termination. By stalling Pol II TECs on the construct we can monitor Sen1-induced termination
in real-time, revealing the formation of an intermediate in which the Pol II transcription …

… Hrp1 as a positive elongation factor on many protein-coding … factor requirements of
Sen1-dependent termination, reminiscent of the diversity of mechanisms for initiation of transcription …