Mechanisms of T-cell activation by human T-cell lymphotropic virus type I

P Hollsberg - Microbiology and Molecular Biology Reviews, 1999 - Am Soc Microbiol
… cell and the subsequent interactions between the infected Tactivation of the infected host
T cell is induced primarily by the viral protein Tax, which influences transcriptional activation, …

Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis

Z Qu, G Xiao - Viruses, 2011 - mdpi.com
… translocation and subsequent transcription activation require degradation of IκBs or processing
of p100 to generate p52, which represent two major mechanisms of NF-κB activation [26]…

Trans-Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

JG Sodroski, CA Rosen, WA Haseltine - Science, 1984 - science.org
… The transcription initiation signals for retroviruses lie within … Two subtypes of human T
lymphotropic virus (HTLV) are … subtypes tofunction as transcriptional elements in differentiated cell …

Critical role of human T-lymphotropic virus type 1 accessory proteins in viral replication and pathogenesis

B Albrecht, MD Lairmore - Microbiology and molecular biology …, 2002 - Am Soc Microbiol
… Much of the work on HTLV-1-mediated T-cell activation and transformation has focused on
the role of the transcriptional activator Tax, which potently activates numerous cellular genes …

Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III

CA Rosen, JG Sodroski, WC Goh, AI Dayton, J Lippke… - Nature, 1986 - nature.com
viral proteins and heterologous proteins under the control of long terminal repeat sequences
of human T-lymphotropic virus … the HTLV-III trans-activator protein. Increased levels of …

In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax

S Paca-Uccaralertkun, LJ Zhao, N Adya… - … and Cellular Biology, 1994 - Taylor & Francis
… the HTLV-I genome is a transcriptional activator (6). Tax does … other viral transactivators such
as herpes simplex virus VP16 … the transcriptional activation of human T-cell leukemia virus

Making sense out of antisense transcription in human T-cell lymphotropic viruses (HTLVs)

B Barbeau, JM Mesnard - Viruses, 2011 - mdpi.com
… HBZ is nuclear factor containing a transcriptional activation domain at its N-terminus and a
ZIP … these proteins from activating transcription of AP-1-dependent promoters by sequestering …

Activation of Nuclear Factor of Activated T Cells by Human T-Lymphotropic Virus Type 1 Accessory Protein p12I

B Albrecht, CD D'Souza, W Ding… - Journal of …, 2002 - Am Soc Microbiol
… cells transfected with pME (not shown) or pME-p12 were fixed and stained for p12 I ,
endogenously expressed calreticulin, or the nuclear transcriptional activator p300. HTLV-1 p12 I …

Transcriptional activation of JC virus by human T-lymphotropic virus type I Tax protein in human neuronal cell lines

…, A Takada, S Suzuki, H Hasegawa, T Umemura… - Journal of Biological …, 2000 - ASBMB
… of human T-lymphotropic virus type I (… transcriptional activation of the JCV promoter. HTLV-I
regulatory protein Tax is a 40-kDa protein that is known to activate several cellular and viral

Human T-Lymphotropic Virus Type 1 p30IIFunctions as a Transcription Factor and Differentially Modulates CREB-Responsive Promoters

W Zhang, JW Nisbet, JT Bartoe, W Ding… - Journal of …, 2000 - Am Soc Microbiol
… expressed, this viral protein may successfully promote viral transcription while … transcriptional
activity. We believe that p30 II functions in infected cells as either a transcriptional activator