… human microglia across a diverse set of clinical pathologies. We demonstrate the human
microglial … of microglia diversity, defines a reference dataset of microglial expression and …

… To investigate whether a similar overlap between the cellular and nuclear transcriptomes
was present in human microglia, we isolated microglia and microglia nuclei from fresh post-…

… Here we report the transcriptional profile of human microglia, isolated from normal-appearing
grey matter (GM) and white matter (WM) of multiple sclerosis (MS) and non-neurological …

… microglial phenotypes more prevalent in AD cases compared with controls. Further, we
describe the heterogeneity in microglia … of microglia in human AD brain can provide insight into …

… Microglia phenotypes are highly regulated by the brain environment, but the transcriptional
networks that specify the maturation of human … and postnatal human microglia and acquired …

… studies of microglial heterogeneity from mice to humans, we … microglia that were isolated
from surgically resected human … transcriptionally distinguishable subpopulations of microglia …

… activation, as well as in a gene set associated with human microglial ageing [43]. Trends
towards increased numbers of nuclei in the Micro2 and PVM sub-clusters were found with both …

… microglial heterogeneity, we also present novel RNA expression profile data that are consistent
with the development of distinct microglial … microglia have regionally distinct transcription …

… conserved features between rodent and human microglia, the importance of … human brain.
We therefore set out to define and validate a core transcriptional signature of human microglia …

… human microglial samples across multiple disease pathologies. We demonstrate that
transcriptional heterogeneity in human microglia … and sQTLs in microglia and thereby validated …