… We reanalyzed the transcriptomic landscape of 1,223 BCP ALLs and identified 14 subgroups
based on their transcriptional profiles. Eight of these (G1 to G8) are previously well-known …

… The differentiation of αβT cells from thymic precursors is a complex process essential for …
of thymic precursors gives rise to mature T cell transcriptomes. We found that early T …

… We discovered that HSCs exist in only three distinct transcriptional states during … the
transcriptional signature of their endothelial precursors. Ultimately, we compared the transcriptional …

… Here we investigate the transcriptional dynamics of mouse organogenesis at single-cell …
We explore the dynamics of gene expression within cell types and trajectories over time, …

… Using single-cell RNA-Seq, we show that existing approaches to stratify bone marrow
CD34+ cells reveal a hierarchically-structured transcriptional landscape of hematopoietic …

… DLX1 and DLX2, homeobox transcription factors essential for interneuron migration and …
transcriptional programs associated with these cells in both structures are highly similar. …

… transcriptional landscape across the cell cycle. We revealed lag between transcription and
steady-state RNA expression at the cell-… amount of active transcription during early mitosis. In …

… , our genome-wide compilation of subcellular localized and product-precursor-related
RNAs serves as a public resource and reveals new and detailed facets of the RNA landscape. …

We aimed at identifying the developmental stage at which leukemic cells of pediatric T‐ ALL
s are arrested and at defining leukemogenic mechanisms based on ATAC ‐Seq. Chromatin …

… as a hematopoietic stem cell that can give rise to all possible blood cell types, eventually
through a committed T cell precursor that can still generate multiple classes of T cell, through a …