The HBP1 transcriptional repressor and the p38 MAP kinase: unlikely partners in G1 regulation and tumor suppression

AS Yee, EK Paulson, MA McDevitt, K Rieger-Christ… - Gene, 2004 - Elsevier
… protein 1 (HBP1) transcriptional repressor and its roles in cell … HBP1 transcription factor and
the p38 MAP kinase pathway—… and connection of the p38 MAP kinase-signaling pathway in …

[HTML][HTML] Inhibition of NF-κB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK

EM King, NS Holden, W Gong, CF Rider… - Journal of Biological …, 2009 - ASBMB
transcription and IL-8 protein, mRNA, and unspliced RNA (a surrogate of transcription rate)
are sensitive to p38 MAPK … ), we explored the role of MKP-1 in repression of these outputs. …

[HTML][HTML] p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene

SK Zaidi, WJ Shen, S Bittner, A Bittner… - Journal of molecular …, 2014 - ncbi.nlm.nih.gov
p38 MAPKs in the regulation of StAR gene transcription using model steroidogenic cell lines.
Our data show that oxidant activation of p38 MAPK … inhibition of p38 MAPK or in cells with …

The transcriptional repressor HBP1 is a target of the p38 mitogen-activated protein kinase pathway in cell cycle regulation

M Xiu, J Kim, E Sampson, CY Huang… - … and cellular biology, 2003 - Am Soc Microbiol
… In this paper, we have identified the HBP1 transcriptional repressor as a p38 MAP kinase
the HBP1 transcriptional repressor and of its regulatory mechanism by the p38 MAP kinase is …

[PDF][PDF] SnapShot: p38 MAPK substrates

N Trempolec, N Dave-Coll, AR Nebreda - Cell, 2013 - cell.com
… The best-characterized MAPK docking site is the D domain, which consists of two or
more basic residues and a stretch of hydrophobic residues with a short linker in between. …

[HTML][HTML] Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase

Z Szatmáry, MJ Garabedian, J Vilcek - Journal of Biological Chemistry, 2004 - ASBMB
Transcriptional Activation—In the next set of experiments, we examined the role of p38 MAP
kinase… actions, in the inhibition of GR-dependent transcriptional activation. The cells were co-…

[HTML][HTML] Activation and signaling of the p38 MAP kinase pathway

T Zarubin, J Han - Cell research, 2005 - nature.com
… half of p38 substrates identified so far are transcription factors… cell cycle progression through
repression of cell cycle regulatory … p38 MAPKs also have the ability to activate other kinases …

Regulation of skeletal muscle gene expression by p38 MAP kinases

F Lluís, E Perdiguero, AR Nebreda… - Trends in cell …, 2006 - cell.com
… how p38 MAPK controls the transcriptional circuitry that underlies tissue-specific gene … these
being generally associated with transcriptional repression. Mammalian HDACs are grouped …

Mechanisms and functions of p38 MAPK signalling

A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
p38 MAPKs are emerging as important modulators of gene expression by regulating … factor
MyoD and the histone methyltransferase KMT1A, which act together in a complex to repress

Transcriptional regulation by the MAP kinase signaling cascades

SH Yang, AD Sharrocks, AJ Whitmarsh - Gene, 2003 - Elsevier
… factors contain phosphorylation-dependent TADs, and in a few cases, phosphorylation-dependent
transcriptional repression domains. The precise mechanisms by which …