102. Elucidating the genomic landscape of Prostate Adenocarcinoma through whole genome and transcriptome sequencing

M Melas, H Geiger, ST Srinivasa, S Guha, V Felice… - Cancer Genetics, 2022 - Elsevier
… cases, RNA sequencing revealed the same known prostate cancer fusion, … cancer type
which could only be identified by WGTS, and with different therapeutic options for the same cancer

Whole-genome sequence of the metastatic PC3 and LNCaP human prostate cancer cell lines

I Seim, PL Jeffery, PB Thomas… - G3: Genes …, 2017 - academic.oup.com
… In addition, transcriptome data from normal prostate samples were obtained from TCGA (see
above). Briefly, paired-end reads were trimmed using scythe, and aligned to human …

The impact of genomic alterations on the transcriptome: a prostate cancer cell line case study

J Chaudhary, M Schmidt - Chromosome Research, 2006 - Springer
transcriptome of prostate cancer cell line DU145. The genomic loss/gain map obtained through
BAC array-based CGH was superimposed on the dynamic transcriptomeprostate cancer

[HTML][HTML] Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer

NM White, CR Cabanski, JM Silva-Fisher, HX Dang… - Genome biology, 2014 - Springer
Transcriptome sequencing, or RNA-Seq, offers an unbiased approach for annotating …
in a cohort of 102 prostate cancer patients, of which 121 were associated with progression [6]. …

Abstract A029: Whole genome and transcriptome analysis of paired metastatic biopsies identified resistance mechanisms in castration-resistant prostate cancer

X Zhu, D Vis, M Sjöström, R Shrestha, J Kneppers… - Cancer Research, 2023 - AACR
… We performed whole-genome sequencing (WGS) and RNA-seq on these samples and …
sequencing data of transcription factors known to be important in prostate cancer (AR, FOXA1, …

Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities

DW Craig, JA O'Shaughnessy, JA Kiefer, J Aldrich… - Molecular cancer …, 2013 - AACR
… Here, we present initial analyses of whole genome and transcriptome sequencing data from
14 prospective mTNBC. We have cataloged the collection of somatic genomic alterations in …

[HTML][HTML] Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European genetic ancestry

J Yuan, KH Kensler, Z Hu, Y Zhang, T Zhang… - PLoS …, 2020 - journals.plos.org
… We report substantial heterogeneity in the prostate tumor genome and transcriptome between
EA and AA. These differences may be biological contributors to racial disparities in CaP …

[HTML][HTML] Integration of metabolomics and transcriptomics reveals major metabolic pathways and potential biomarker involved in prostate cancer

S Ren, Y Shao, X Zhao, CS Hong, F Wang, X Lu… - Molecular & Cellular …, 2016 - ASBMB
… ), which were correlated with tumor grade, stage, and preoperative prostate-specific antigen
(PSA) levels. Transcriptome sequencing across a PCa cohort identified that PCAT-1 was …

CTPC, a combined transcriptome data set of human prostate cancer cell lines

S Cheng, X Yu - The Prostate, 2023 - Wiley Online Library
Prostate cancer (PCa) is one of the most common cancers in American men and the
second leading cause of cancer-related deaths. Cell line models are commonly used in PCa …

[HTML][HTML] … of unique PMEPA1 gene splice variants (isoforms d and e) from RNA Seq profiling provides novel insights into prognostic evaluation of prostate cancer

S Sharad, AA Dillman, ZM Sztupinszki, Z Szallasi… - Oncotarget, 2020 - ncbi.nlm.nih.gov
Prostate cancer is a disease with heterogeneity of multiple gene transcriptomes and …
VCaP, LNCaP cells and human prostate cancer samples from The Cancer Genome Atlas (TCGA) …