Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl
S Grond, L Radbruch, KA Lehmann - Clinical pharmacokinetics, 2000 - Springer
… of sustained release morphine had to be increased only slightly from 156 to 174 mg/day in
the intermediate treatment period, whereas the initial dosage of transdermal fentanyl had to …
the intermediate treatment period, whereas the initial dosage of transdermal fentanyl had to …
Transdermal fentanyl therapy: system design, pharmacokinetics and efficacy
MA Southam - Anti-Cancer Drugs, 1995 - journals.lww.com
… was in the range 315–404 mg was prescribed a TTS fentanyl dose of 100 ug/h. They were
… TTS fentanyl dose. The analgesic outcome was evaluated after 1 month of TTS fentanyl …
… TTS fentanyl dose. The analgesic outcome was evaluated after 1 month of TTS fentanyl …
Pharmacokinetics of non-intravenous formulations of fentanyl
J Lötsch, C Walter, MJ Parnham, BG Oertel… - … pharmacokinetics, 2013 - Springer
… Nowadays, transdermal fentanyl patches are among the most frequently prescribed strong
… entire dose within a short period of time [74]. Therefore, current passive transdermal fentanyl …
… entire dose within a short period of time [74]. Therefore, current passive transdermal fentanyl …
The transdermal administration of fentanyl in the treatment of postoperative pain: pharmacokinetics and pharmacodynamic effects
GK Gourlay, SR Kowalski, JL Plummer, DA Cherry… - Pain, 1989 - Elsevier
… calculate the fentanyl dose rate to be applied to each patient: … at least 1 h before blood fentanyl
concentrations from the TTS … The transdermal fentanyl dose for the second 24 h was kept …
concentrations from the TTS … The transdermal fentanyl dose for the second 24 h was kept …
Pharmacokinetics of fentanyl following intravenous and transdermal administration in horses
LK Maxwell, SM Thomasy, N Slovis… - Equine veterinary …, 2003 - Wiley Online Library
… citrate (0.05 mg/ml) administered iv by jugular venipuncture, and 3 horses received Treatment
B, which consisted of a 20 mg dose of fentanyl administered transdermally via two 10 mg …
B, which consisted of a 20 mg dose of fentanyl administered transdermally via two 10 mg …
Postoperative analgesia with fentanyl: pharmacokinetics and pharmacodynamics of constant-rate iv and transdermal delivery
FO Holley, C Van Steennis - BJA: British Journal of Anaesthesia, 1988 - academic.oup.com
… fentanyl would be suitable for transdermal drug delivery, we first tested the efficacy and safety
of fentanyl … that delivery of analgesic doses of fentanyl is feasible by 'the transdermal route. …
of fentanyl … that delivery of analgesic doses of fentanyl is feasible by 'the transdermal route. …
Transdermal fentanyl: pharmacokinetics and preliminary clinical evaluation
PM Plezia, TH Kramer, J Linford… - … : The Journal of …, 1989 - Wiley Online Library
… Several clinically useful agents are now available in transdermal dosage forms that allow …
patient compliance as a result of longer dosing intervals and less frequent administration.’ …
patient compliance as a result of longer dosing intervals and less frequent administration.’ …
Comparison of pharmacokinetics of fentanyl after intravenous and transdermal administration in cats
DD Lee, MG Papich, EM Hardie - American journal of veterinary …, 2000 - Am Vet Med Assoc
… was not dose-dependent and did not change between IV and patch administration.
Studies11,13,21 in other animals have revealed that pharmacokinetics of fentanyl is not dose-…
Studies11,13,21 in other animals have revealed that pharmacokinetics of fentanyl is not dose-…
Transdermal fentanyl: clinical pharmacology
KA Lehmann, D Zech - Journal of pain and symptom management, 1992 - Elsevier
… The single- and multiple-dose pharmacokinetics of TTS fentanyl have been evaluated by
several teams in postoperative and cancer patients and were found to be remarkably …
several teams in postoperative and cancer patients and were found to be remarkably …
Transdermal fentanyl: an overview of pharmacokinetics, efficacy and safety
M Southam, S Gupta, M Knowles, SS Hwang - Transdermal Fentanyl: A …, 1991 - Springer
… integrated overview of the pharmacokinetics, efficacy, and safety of TTS fentanyl.
Pharmacokinetics The single- and multiple-dose pharmacokinetics of TTS fentanyl were evaluated in …
Pharmacokinetics The single- and multiple-dose pharmacokinetics of TTS fentanyl were evaluated in …
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