Models of HIV type 1 proviral gene expression in wild-type HIV and MLV/HIV transgenic mice

P Dickie, R GAZZINELLI, LJI CHANG - AIDS research and human …, 1996 - liebertpub.com
HIV transgenic mice are compared in this article. Our purpose is to present these two HIV
transgenic … the six HIV proviral mice generated in this study expressed HIV RNA (not shown), …

HIV type-1 transgene expression in mice alters adipose tissue and adipokine levels: towards a rodent model of HIV type-1 lipodystrophy

J Villarroya, J Diaz-Delfin, D Hyink, P Domingo… - 2010 - journals.sagepub.com
HIV-1 transgene expression in mice causes changes in adipose tissue reminiscent of those
in patients with HIV-1 … These data support a role for HIV-1-infection-related events in eliciting …

Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease

Z Hanna, DG Kay, M Cool, S Jothy, N Rebai… - Journal of …, 1998 - Am Soc Microbiol
We have constructed transgenic (Tg) mice expressing the entire human immunodeficiency
virus type 1 (HIV-1) coding sequences in cells targeted by HIV-1 infection in humans. These …

HIV transgene expression impairs K+ channel function in the pulmonary vasculature

G Mondejar-Parreño, D Morales-Cano… - … of Physiology-Lung …, 2018 - journals.physiology.org
… of and activity of voltage-gated K + channel 7.1 (Kv7.1) in pulmonary arteries from human
immunodeficiency virus type 1 transgenic (Tg26) mice. A: voltage-gated K + channel subfamily …

Sustained transgene expression using MAR elements

N Harraghy, A Gaussin, N Mermod - Current gene therapy, 2008 - ingentaconnect.com
human immunodeficiency virus type 1 (HIV-1). The RevM10 transgene has been found to
inhibit HIV-… T cells, although high levels of expression are required for the anti-HIV effect [111]. …

Specific transgene expression in HIV-infected cells using protease-cleavable transcription regulator

D Asai, M Kuramoto, Y Shoji, JH Kang… - Journal of controlled …, 2010 - Elsevier
… to achieve highly specific transgene expression in HIV-infected cells… HIV-Tat peptide via a
specific substrate for HIV-1 protease. The regulator formed a stable polyplex with the transgene

Nef modulation of HIV type 1 gene expression and cytopathicity in tissues of HIV transgenic mice

P Dickie - AIDS research and human retroviruses, 2000 - liebertpub.com
Transgenic mice bearing HIV-1 proviral DNA deleted in the gag/pol region (… expression in
various cell types including macrophages. They display a disease phenotype that includes HIV-…

High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors

P Salmon, V Kindler, O Ducrey… - Blood, The Journal …, 2000 - ashpublications.org
… Correspondingly, lentiviral vectors derived from human immunodeficiency virus type 1 (HIV-…
expression of transgenes into nonmitotic cells both in vitro and in vivo.11-13 In particular, HIV

Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

S Philippe, C Sarkis, M Barkats… - Proceedings of the …, 2006 - National Acad Sciences
HIV vectors for expressing transgenes in vitro and in vivo. We have developed a HIV type 1
(HIV… that this vector drives efficient transgene expression in dividing and nondividing cells in …

CD4-Specific Transgenic Expression of Human Cyclin T1 Markedly Increases Human Immunodeficiency Virus Type 1 (HIV-1) Production by CD4+ T Lymphocytes …

J Sun, T Soos, VN KewalRamani, K Osiecki… - Journal of …, 2006 - Am Soc Microbiol
HIV LTR regulating the HIV transgene in our transgenic mice, resulting in the production of
higher levels of HIV proteins deleterious to tissues in their transgenicHIV proviral transgene