Transgenic cell lines for detection of animal viruses

PD Olivo - Clinical microbiology reviews, 1996 - Am Soc Microbiol
… Likewise, the development of animal cell culture techniques was critical to the field of animal
virology, since it … Primary cell lines could then be harvested from transgenic animals. These …

Embryonic stem cells, creating transgenic animals

M Pirity, AK Hadjantonakis, A Nagy - Methods in cell biology, 1998 - Elsevier
… new ES cell lines through genetically altering the cells to deriving transgenic animals, can be
done … tissue culture and having access to an animal facility. Details regarding setting up an …

Use of transgenic animals in biotechnology: prospects and problems

OG Maksimenko, AV Deykin… - Acta Naturae …, 2013 - cyberleninka.ru
… isolated from the milk of transgenic animals, C1 inhibitor (… applied to produce transgenic
animals are described and the … (based on transgenic animals and mammalian cell cultures) …

Transcriptional control of the human apolipoprotein B gene in cell culture and in transgenic animals

B Levy-Wilson - Progress in nucleic acid research and molecular …, 1995 - Elsevier
cell culture versus transgenic animals almost certainly reflects the effect of integration of the
transgene … Thus, the lack of expression in transgenic animals may result from a requirement …

Physiology and Pathophysiology of α‐Synuclein: Cell Culture and Transgenic Animal Models Based on a Parkinson's Disease‐associated Protein

PJ Kahle, M Neumann, L Ozmen… - Annals of the New York …, 2000 - Wiley Online Library
… Human-specific antibodies are indispensable in the study of transgenic animals expressing
… SYN in brain, we generated transgenic mice. Strong expression of transgenic human [A30P]α…

Transgenic animals in biomedical research

GT Merlino - The FASEB journal, 1991 - Wiley Online Library
Transgenic animals created by these genetic manipulations … Furthermore, transgenic
biotechnology holds great promise for … It is evident now that the study and use of transgenic

Steroid hormone regulation and tissue-specific expression of the human GnRH gene in cell culture and transgenic animals

S Radovick, S Wray, L Muglia, H Westphal… - Hormones and …, 1994 - Elsevier
… to the luciferasc (Luc) reporter gene, and transgenic mice generated. Expression in …
transgenic animals was found in the hypothalamus of animals bearing the —-50l]ULuc transgene

Gene transfer and expression in mammalian cell lines and transgenic animals

F Recillas-Targa - Recombinant Gene Expression: Reviews and …, 2004 - Springer
cell lines or in transgenic animals. Such kinds of studies can be supported by the use of primary
cell cultures … also take advantage of transformed cell lines derived from viral infections or …

Transgenic animals as bioproducers of therapeutic proteins

J Jänne, JM Hyttinen, T Peura, M Tolvanen… - Annals of …, 1992 - Taylor & Francis
… also in large-scale animal cell cultures. Although extremely cost-… employing large-scale
animal cell cultures for the production … for rich culture media, the use of animal cell bioreactors is …

Multiple strategies for gene transfer, expression, knockdown, and chromatin influence in mammalian cell lines and transgenic animals

F Recillas-Targa - Molecular biotechnology, 2006 - Springer
… in different types of cultured cell lines or in transgenic animals (discussed later). Those
studies can be supported by the use of primary cell cultures from various organisms and tissues, …