… transgene was not transmitted through the germ line. Over the past several years, we have
produced transgenic mice … drive HBV expression and replication at levels comparable to that …

… replication or its maturation in transgenic mice, it can enhance viral replication, apparently by
activating viral … a transactivation role of the X protein in HBV replication in transgenic mice. …

… To test this hypothesis, we crossed transgenic mice that replicate HBV with mice that are
genetically deficient for IRF-1, RNase L, or PKR (IRF-1 −/− , RNase L −/− , or PKR −/− mice, …

… Hepatitis B virus is generally accepted to be a hepatotropic, noncytopathic virus.1 In this
study, an HBV-constructed transgenic mouse model, with active replication of HBV-DNA and …

… indicate that hepatitis B virus (HBV) may induce autophagy to enhance its replication in cell
… can indeed enhance HBV replication in vivo, we generated HBV transgenic mice with liver-…

… hepatitis B virus (HBV) replication and gene expression are abolished in the livers of HBV
transgenic mice … CTLs) and during lymphocytic choriomeningitis virus (LCMV) infection, stimuli …

We produced transgenic mice by microinjecting a partial tandem duplication of the complete
hepatitis B virus (HBV) genome into … gene expression, allowing viral replication. Thus, these …

… , transgenic mice that express the hepatitis B virus core and precore proteins under the
transcriptional control of the liver-specific mouse … hepatitis B virus replication in transgenic mice. J …

… hepatitis B virus (HBV) by using transgenic mice obtained after injection of head-to-tail dimers
of the HBV genome. Viral DNA replication … the study of many aspects of viral multiplication. …

… viral replication in these animals. We also crossed lineages 1.3.32 and 1.3.46 with two
independent lineages of transgenic mice … - or 2.1-kb viral RNA transcript or on viral replication (not …