Recent progress in the use of mitochondrial membrane permeability transition pore in mitochondrial dysfunction-related disease therapies
Y Cui, M Pan, J Ma, X Song, W Cao… - Molecular and Cellular …, 2021 - Springer
… and summarizes the mitochondrial dysfunction-correlated diseases and … mitochondrial
dysfunction, this review also summarizes potential treatments, which may be used to inhibit pore …
dysfunction, this review also summarizes potential treatments, which may be used to inhibit pore …
Mitochondria and aging: A role for the mitochondrial transition pore?
M Panel, B Ghaleh, D Morin - Aging cell, 2018 - Wiley Online Library
… features of mitochondrial physiology and dysfunction have been … role of the mitochondrial
permeability transition pore (mPTP) in … , thus reinforcing mitochondrial dysfunction (Figure 2). …
permeability transition pore (mPTP) in … , thus reinforcing mitochondrial dysfunction (Figure 2). …
[HTML][HTML] Diabetes Mellitus, Mitochondrial Dysfunction and Ca2+-Dependent Permeability Transition Pore
KN Belosludtsev, NV Belosludtseva… - International journal of …, 2020 - mdpi.com
… the role of mitochondrial dysfunction in the development of … of mitochondrial calcium
transport systems and a pathophysiological phenomenon called the permeability transition pore in …
transport systems and a pathophysiological phenomenon called the permeability transition pore in …
[HTML][HTML] Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle
EP Taddeo, RC Laker, DS Breen, YN Akhtar… - Molecular …, 2014 - Elsevier
… mitochondrial permeability transition pore (mPTP). The mPTP is a multi-protein complex that
spans both mitochondrial … Da between the cytoplasm and mitochondrial matrix. Importantly, …
spans both mitochondrial … Da between the cytoplasm and mitochondrial matrix. Importantly, …
[HTML][HTML] Mitochondrial dysfunction and alterations in mitochondrial permeability transition pore (mPTP) contribute to apoptosis resistance in idiopathic pulmonary …
ER Luis-García, C Becerril, A Salgado-Aguayo… - International journal of …, 2021 - mdpi.com
… To investigate whether apoptosis resistance in IPF fibroblasts is associated with mitochondrial
dysfunction, we analyzed the integrity of mitochondria through oxygen consumption in IPF …
dysfunction, we analyzed the integrity of mitochondria through oxygen consumption in IPF …
[HTML][HTML] Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of patients with sporadic Alzheimer's disease
MJ Pérez, DP Ponce, A Aranguiz, MI Behrens… - Redox Biology, 2018 - Elsevier
… mitochondrial calcium uptake by the mitochondrial … mitochondrial failure in AD fibroblasts.
These findings suggest that peripheral cells present similar signs of mitochondrial dysfunction …
These findings suggest that peripheral cells present similar signs of mitochondrial dysfunction …
The molecular composition of the mitochondrial permeability transition pore
CP Baines - Journal of molecular and cellular cardiology, 2009 - Elsevier
… The discovery that mitochondrial dysfunction is often a … studying the mitochondrial permeability
transition pore and its … molecular composition of the mitochondrial pore, and the purpose …
transition pore and its … molecular composition of the mitochondrial pore, and the purpose …
[HTML][HTML] The mitochondrial permeability transition pore in AD 2016: An update
… Paraplegia 7 (SPG7), a mitochondrial AAA-type membrane protease which forms … mitochondrial
permeability transition pore. This article is part of a Special Issue entitled: Mitochondrial …
permeability transition pore. This article is part of a Special Issue entitled: Mitochondrial …
Physiological roles of the permeability transition pore
… homeostasis is tightly regulated, and mitochondrial dysfunction is frequently associated with
severe human pathologies (eg, cardiovascular diseases, cancer, and neurodegeneration). …
severe human pathologies (eg, cardiovascular diseases, cancer, and neurodegeneration). …
[HTML][HTML] Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology
… When mitochondria are exposed to a pathological overload of … of the mitochondrial
permeability transition pore complex (… Recently, mitochondrial dysfunction has been increasingly …
permeability transition pore complex (… Recently, mitochondrial dysfunction has been increasingly …
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