Therapeutic angiogenesis for peripheral artery disease: lessons learned in translational science

SR Iyer, BH Annex - Basic to translational science, 2017 - jacc.org
Angiogenesis is the growth and proliferation of blood vessels from existing vasculature. For
approximately 2 decades, “therapeutic angiogenesis… field of therapeutic angiogenesis stands …

The complexity of translating anti-angiogenesis therapy from basic science to the clinic

W Ye - Developmental cell, 2016 - cell.com
… of anti-angiogenesis therapy and medical reality … angiogenesis concept and apply this
perspective to a careful evaluation of the preclinical and clinical outcomes of anti-angiogenesis

Forty-year journey of angiogenesis translational research

Y Cao, J Arbiser, RJ D'Amato, PA D'Amore… - Science translational …, 2011 - science.org
… 40 years of angiogenesis research and discuss challenges of antiangiogenic therapy. …
the isolation of an angiogenesis-promoting activity called tumor angiogenesis factor (TAF) that …

New directions in therapeutic angiogenesis and arteriogenesis in peripheral arterial disease

BH Annex, JP Cooke - Circulation research, 2021 - Am Heart Assoc
therapeutic angiogenesis or medical revascularization. Perhaps, a better term is vascular
regeneration, which encompasses angiogenesis, … Investigation into therapeutic angiogenesis

Translating angiogenesis research into the clinic: the challenges ahead

HG Augustin - The British Journal of Radiology, 2003 - academic.oup.com
… It will then provide an overview of the current concepts of the angiogenic … the translational
angiogenesis community in order to rationally implement anti-angiogenic tumour therapies into …

Angiogenesis research: guidelines for translation to clinical application

J Folkman, T Browder… - Thrombosis and …, 2001 - thieme-connect.com
… Further, angiogenesis is modulated by proteins and cells from the hematopoietic and … of
angiogenesis inhibitors has accentuated the need for surrogate markers of tumor angiogenesis

Therapeutic angiogenesis: translating experimental concepts to medically relevant goals

C Emanueli, P Madeddu - Vascular pharmacology, 2006 - Elsevier
therapeutic angiogenesis for the cure of myocardial and peripheral ischemia. Therapeutic
angiogenesis aims at combating the insufficiency of, or insensitivity to angiogenic factors in …

The quest for surrogate markers of angiogenesis: a paradigm for translational research in tumor angiogenesis and anti-angiogenesis trials

C Ruegg, JY Meuwly, R Driscoll… - Current molecular …, 2003 - ingentaconnect.com
… This study illustrates well one of the main problems in anti-angiogenesis therapy, eg … the
need for surrogate markers of angiogenesis to monitor the angiogenic status and drug efficacy. …

Angiogenesis: from molecular mechanisms to translational implications

B Li, R Xiu - Clinical hemorheology and microcirculation, 2013 - content.iospress.com
Scientists believe that angiogenesis may be a rate… Therapeutic angiogenesis for myocardial
ischemia revisited: Basic biological concepts and focus on latest clinical trials, Angiogenesis

Basic and therapeutic aspects of angiogenesis updated

G Eelen, L Treps, X Li, P Carmeliet - Circulation research, 2020 - Am Heart Assoc
… and acquired therapy resistance. Tumors cunningly deploy alternative growth factors than
the ones targeted by the antiangiogenic therapies to reinstigate angiogenesis or revert to …