Performance of an ultra-sensitive Plasmodium falciparum HRP2-based rapid diagnostic test with recombinant HRP2, culture parasites, and archived whole blood …

S Das, RB Peck, R Barney, IK Jang, M Kahn, M Zhu… - Malaria journal, 2018 - Springer
… assess uRDT performance in endemic areas. Recently, the … a low transmission area with
parasitaemia and HRP2 ranging … a high transmission area with parasitaemia and HRP2 ranging …

HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions

A Kong, SA Wilson, Y Ah, D Nace, E Rogier, M Aidoo - Malaria Journal, 2021 - Springer
… -conjugated beads), a density often associated with asymptomatic infection in high transmission
settings, HRP2 bands on all three RDTs were positive, although at low band intensities (…

Performance of HRP-2 based rapid diagnostic test for malaria and its variation with age in an area of intense malaria transmission in southern Tanzania

A Laurent, J Schellenberg, K Shirima, SC Ketende… - Malaria journal, 2010 - Springer
… When HRP-2 tests are used for primary diagnosis in area of intense transmission, our
results suggest a risk of malaria over-diagnosis in children, which might have serious …

Evaluation of an ultrasensitive HRP2–based rapid diagnostic test for detection of asymptomatic Plasmodium falciparum parasitaemia among children in western …

LB Turnbull, G Ayodo, V Knight, CC John, MS McHenry… - Malaria Journal, 2022 - Springer
… is lower than we report for symptomatic adults in low- transmission areas [17], this difference
in performance may be related to the lower level of malaria exposure and immunity in the …

False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission

CT Kozycki, N Umulisa, S Rulisa, EI Mwikarago… - Malaria journal, 2017 - Springer
… the sensitivity of HRP2 RDTs at 3 sites with varying intensities of transmission in Rwanda to
HRP2 RDT after a fall in malaria transmission. In Rukara, monthly estimates of HRP2 RDT

Lessons learned from the use of HRP-2 based rapid diagnostic test in community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in …

AB Tiono, A Ouédraogo, A Diarra, S Coulibaly… - Malaria journal, 2014 - Springer
… The specificity of HRP-2 tests raises concerns in areas of intense malaria transmission
due … The aim of this paper is to report HRP-2 based RDT results from a recent cluster-randomized …

Factors affecting the performance of HRP2-based malaria rapid diagnostic tests

X Martiáñez-Vendrell, M Skjefte, R Sikka… - Tropical Medicine and …, 2022 - mdpi.com
… of type 2 repeats and poor HRP2 RDT diagnosis (p = 0.046). … non-sensitive to HRP2 RDTs
based on HRP2 sequence for the … performance of RDTs in areas of low malaria transmission […

Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

V Briand, G Cottrell, N Tuike Ndam… - Malaria journal, 2020 - Springer
… In conclusion, these results are complementary to those previously reported in a low malaria
transmission area. They confirm the higher overall performance of uRDT, compared to the …

Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali

EN Reichert, JCC Hume, I Sagara, SA Healy… - Malaria Journal, 2020 - Springer
… -sensitive HRP2-based Alere™ Malaria Ag Pf RDT (uRDT). The samples were collected
as part of a transmission-blocking vaccine trial in a high transmission region for Plasmodium …

Accuracy of HRP2 RDT (Malaria Antigen Pf®) compared to microscopy and PCR for malaria diagnosis in Senegal

B Faye, M Nath-Chowdhury, RC Tine… - Pathogens and global …, 2013 - Taylor & Francis
… in low transmission areas such as Senegal or by the genetic diversity of gene HRP2 in these
… prevalence in gene HRP2 in false negative patients with the ParaSight RDT. Citation23 …