The in-vivo dynamics of Plasmodium falciparum HRP2: implications for the use of rapid diagnostic tests in malaria elimination

L Marquart, L Webb, P O'Rourke, ML Gatton… - Malaria journal, 2022 - Springer
… re-infection in high transmission settings. Additionally, developing … of hrp2/hrp3 deletion,
and a growing reliance on RDTs … -based RDTs, including usRDTs, in low transmission and pre…

Use of a rapid test to assess plasma Plasmodium falciparum HRP2 and guide management of severe febrile illness

I Sinha, N Ekapirat, AM Dondorp, CJ Woodrow - Malaria journal, 2015 - Springer
… of plasma PfHRP2 in a high transmission setting might be achieved using a single RDT. …
that a single RDT can be used to obtain useful information on plasma HRP2 concentration and …

Evaluation of wondfo rapid diagnostic kit (Pf-HRP2/PAN-pLDH) for diagnosis of malaria by using nano-gold immunochromatographic assay

J Wu, Y Peng, X Liu, W Li, S Tang - Acta Parasitologica, 2014 - Springer
… falciparum target HRP-2, only few of them are designed to detect Pf-pLDH. We have … RDTs
for detecting HRP-2 and pan-pLDH in an area of intense and perennial malaria transmission

Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity

GS Williams, C Mweya, L Stewart, G Mtove, H Reyburn… - Malaria journal, 2009 - Springer
… of low transmission [6]. For tests based on HRP-2, the RDT consists of a plastic cassette …
which contains immobilized and gold-labelled anti-HRP-2 antibodies [7]. The test is performed …

Malaria rapid diagnostic tests: challenges and prospects

JC Mouatcho, JPD Goldring - Journal of medical …, 2013 - microbiologyresearch.org
… recent developments in malaria RDTs, reviewing RDTs detecting PfHRP2, pLDH and … Beira,
Mozambique, a low malaria transmission area, a three-line pLDH-based RDT, OptiMAL-IT (…

[PDF][PDF] Assessment of HRP2-Based RDT in Diagnosing Malaria Cases

Y Dieng, D Sow, T Dieng, A Sow, B Faye… - Journal of Life …, 2012 - academia.edu
HRP2-based Rapid Diagnostic Tests (RDTs) for malaria ensure a rational use of
artemisinin-based combination therapy (ACT). The HRP2 … Conclusion: Tests to detect HRP2 in the …

Performance evaluation of the highly sensitive histidine‐rich protein 2 rapid test for Plasmodium falciparum malaria in North-West Tanzania

A Manjurano, JJ Omolo, E Lyimo, D Miyaye… - Malaria Journal, 2021 - Springer
… Recently, manufacturers have developed highly sensitive RDTs based on HRP2transmission
(Geita) areas, with stable transmission intensity. The main peak of malaria transmission

[HTML][HTML] Estimating the added utility of highly sensitive histidine-rich protein 2 detection in outpatient clinics in sub-Saharan Africa

MM Plucinski, E Rogier, PR Dimbu… - The American Journal …, 2017 - ncbi.nlm.nih.gov
… This is particularly important for RDTs detecting HRP2, since HRP2 can be produced in large
… concentration that is unaffected by the range of malaria transmission intensity included in …

Placental Plasmodium falciparum malaria infection: Operational accuracy of HRP2 rapid diagnostic tests in a malaria endemic setting

DJ Kyabayinze, JK Tibenderana, M Nassali… - Malaria journal, 2011 - Springer
… This study compares HRP-2 RDTs to microscopy for detecting peripheral malaria in feverish
… It has been argued that the effectiveness of RDTs is dependent on malaria transmission

Diagnostic accuracy of CareStart™ malaria HRP2 and SD Bioline Pf/PAN for malaria in febrile outpatients in varying malaria transmission settings in Cameroon

IM Ali, AM Nji, JC Bonkum, MN Moyeh, GK Carole… - Diagnostics, 2021 - mdpi.com
… We further compared the diagnostic parameters of Pf mRDTs (HRP-2) against Pf/PAN RDTs
in each of the two facilities in Dschang when both diagnostic tests were performed on the …