… that forms amyloid fibrils … amyloidosis is determined by the amyloid-forming protein and
the organ predilection. This review will focus on transthyretin amyloidosis, a form of amyloidosis …

… Transthyretin amyloid cardiomyopathy (ATTR-CM) is a life-… transthyretin amyloid fibrils in
the heart, and can often be overlooked as a common cause of heart failure. Delayed diagnosis …

… variants of TTR (mutant transthyretin amyloidosis [ATTRm]; also known as hereditary ATTR).
… -positive test from myocardial uptake of the isotope indicative of transthyretin amyloidosis …

… Once a diagnosis of ATTR amyloidosis has been made, genetic testing by TTR gene
sequencing should be performed to establish mutation status. Patients may be referred to an …

… , suspicion, diagnosis, and systematic screening of ATTRwt CM, … in a patient, (ii) how to
diagnose the disease, and (iii) which at‐… part of or a full diagnostic pathway for ATTRwt CM were …

… froin diagnostic testing, genetic counseling, prenatal testing, and treatment such as liver
transplantation. Now we are charged with the task of taking our knowledge base and pursuing …

… , genetic screening for a TTR gene … TTR in cardiac amyloid deposits after LT,74 suggesting
that paradoxical progressive deposition of wild type TTR on pre-existing variant TTR amyloid …

… Transthyretin amyloid … , the diagnosis of ATTR-CM no longer requires invasive evaluation
with tissue biopsy. Here, the authors review current diagnostic tools to help clinicians diagnose …

… The diagnosis of hereditary ATTR amyloidosis is established in … , amyloid deposits identified
on biopsy that bind to anti-TTR … pathogenic variant in TTR by molecular genetic testing. …

… In this review, we focus on the importance of performing the most appropriate testing
strategies for ATTR amyloidosis and establishing a CoE for this rare disease. We highlight our …