… Hereditary transthyretin amyloidosis, once a rare progressive … as a result of mutated
transthyretin amyloid aggregation and … to reduce the production of transthyretin and had promising …

… pharmacological agents that inhibit hepatic synthesis of TTR, stabilize the tetramer, or …
update on this rapidly evolving field, together with practical recommendations on the management …

… 11 Management of cardiovascular … TTR in cardiac amyloid deposits after LT,74 suggesting
that paradoxical progressive deposition of wild type TTR on pre-existing variant TTR amyloid …

… the clinical spectrum and management based on the … TTR amyloid deposits [11]. It should
be noted that both cardiomyopathy and carpal tunnel syndrome due to ATTRwt amyloidosis …

… TTR is … However, TTR monomers can undergo a major conformational transformation to
aggregate in a highly ordered and abnormal amyloid fibril form (Citation3); TTR in its amyloid …

… mutations can be excluded or established on genetic testing, as sequence analysis identifies
>99% of pathogenic variants, with updated lists of TTR mutations and phenotypes reported …

… For patients with systemic ATTR amyloidosis, TTR amyloid detection and characterisation in
… Amyloid nomenclature 2020: update and recommendations by the International Society of …

… At the same time, the development of novel targeted amyloid … to screen asymptomatic
transthyretin amyloidosis gene mutation … advances in treatment for transthyretin amyloidosis‐CA, …

… A substantial increase in the interest in transthyretin cardiac amyloidosis (ATTR-CA) is a …
Wildtype transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction…

… light chain amyloidosis (AL) caused by monoclonal immunoglobulin light chains and
transthyretin amyloidosis (ATTR) caused by either mutated or wild-type transthyretin aggregates. …