… transthyretin familial amyloid polyneuropathy (TTR-FAP) in Europe: where are we now? A
European network approach to defining the epidemiology and management patterns for TTR-…

… a Japanese family presented with peripheral neuropathy and autonomic neuropathy in their
early 40s. Cardiac ainyloid deposits were proven to contain transthyretin amyloid. A French/ …

… promote spreading along the nerve. Thus, progressive accumulation of amyloid fibrils as well
prefibrillar material along the peripheral nerve trunks causes further nerve injury, leading to …

… to the Peripheral Neuropathy Center indeed have neuropathy, we did not confirm this likely
shared … by means of nerve biopsy, confirming the presence of amyloid deposits in the nerve. …

… peripheral nerve alterations in TTR amyloidosis, we designed a systematic study of the upper
and lower limb peripheral nerve … of US to diagnose TTR amyloidosis, to study demographic…

… peripheral neuropathies. The objective of this study, then, was to better understand the natural
history of peripheral neuropathy … the time-course of neuropathic degeneration in ATTRv-…

… series had mild neuropathy, and none had severe neuropathic pain or progressive weakness,
contrasting the rapid progression of hereditary ATTR amyloidosis where many patients …

… Transthyretin amyloidosis (ATTR), previously known as familial amyloid polyneuropathy (TTR-FAP),
is a rare systemic disease due to the preferential peripheral nerve but also cardiac, …

… Peripheral neuropathy occurs in the setting of both hereditary and acquired … Neuropathic
hereditary transthyretin amyloidosis (hATTR) was first described in Portugal in 1952,[6] with …

… high levels of variant TTR amyloid protein; this was similar to those who had neuropathy
symptoms.18 Differences … Peripheral nerve specimens from individuals with TTR FAP revealed …