Neuroinflammation and blood–brain barrier disruption following traumatic brain injury: pathophysiology and potential therapeutic targets
S Sulhan, KA Lyon, LA Shapiro… - Journal of neuroscience …, 2020 - Wiley Online Library
… This review focuses on the mechanisms involved in traumatic brain injury, separating them
… a traumatic brain injury that intimately interplay with disruption of the blood–brain barrier. …
… a traumatic brain injury that intimately interplay with disruption of the blood–brain barrier. …
[HTML][HTML] Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury
EA van Vliet, XE Ndode-Ekane, LJ Lehto… - Neurobiology of …, 2020 - Elsevier
… -head injury and post-traumatic epilepsy. We also investigated association BBB leakage
with neuroinflammation and epileptogenesis. Finally, we assessed human autopsy brain tissue …
with neuroinflammation and epileptogenesis. Finally, we assessed human autopsy brain tissue …
[HTML][HTML] Neuroinflammation in traumatic brain injury: a chronic response to an acute injury
SJ Schimmel, S Acosta, D Lozano - Brain circulation, 2017 - journals.lww.com
… , blood–brain barrier disruption, and inflammation accompany chronic traumatic brain injury
(TBI) and … One hallmark of both acute and chronic TBI is neuroinflammation. In acute stages, …
(TBI) and … One hallmark of both acute and chronic TBI is neuroinflammation. In acute stages, …
The role of neuroinflammation in traumatic brain injury
OI Schmidt, M Infanger, CE Heyde, W Ertel… - … Journal of Trauma, 2004 - Springer
… neuroinflammation is further exacerbated by the subsequent intracranial recruitment of blood…
mechanism of neuroinflammation contributing to secondary brain damage by complement …
mechanism of neuroinflammation contributing to secondary brain damage by complement …
Low cerebral blood flow is a non-invasive biomarker of neuroinflammation after repetitive mild traumatic brain injury
… outcome after repetitive mild traumatic brain injury (rmTBI)… cerebral blood flow and underlying
neuroinflammation. Specifically, because neuroinflammation is a driver of secondary injury …
neuroinflammation. Specifically, because neuroinflammation is a driver of secondary injury …
[HTML][HTML] Brain–immune interactions and neuroinflammation after traumatic brain injury
… of the microglia and astrocytes as well as the blood–brain barrier dysfunction during the
first week after the injury. Considering the neuroinflammatory activity as a causal element of …
first week after the injury. Considering the neuroinflammatory activity as a causal element of …
Traumatic brain injury, neuroinflammation, and post‐traumatic headaches
CL Mayer, BR Huber, E Peskind - … : The Journal of Head and …, 2013 - Wiley Online Library
… increased blood flow, plasma protein leakage from blood vessels, mast cell degranulation,
and platelet aggregation.119 One stimulus for neuroinflammation may be direct injury to the …
and platelet aggregation.119 One stimulus for neuroinflammation may be direct injury to the …
Platelet regulates neuroinflammation and restores blood–brain barrier integrity in a mouse model of traumatic brain injury
C Gao, H Wang, T Wang, C Luo, Z Wang… - Journal of …, 2020 - Wiley Online Library
… accompanied by microglial activation triggers multiple cell death after traumatic brain injury
(… ‐2 regulates trauma‐induced neuroinflammation and restores blood–brain barrier integrity. …
(… ‐2 regulates trauma‐induced neuroinflammation and restores blood–brain barrier integrity. …
Correlations between blood–brain barrier disruption and neuroinflammation in an experimental model of penetrating ballistic-like brain injury
TL Cunningham, CM Cartagena, XCM Lu… - Journal of …, 2014 - liebertpub.com
… Blood–brain barrier (BBB) disruption is a pathological hallmark of severe traumatic brain
injury (TBI) and is associated with neuroinflammatory events contributing to brain edema and …
injury (TBI) and is associated with neuroinflammatory events contributing to brain edema and …
[HTML][HTML] Single mild traumatic brain injury induces persistent disruption of the blood-brain barrier, neuroinflammation and cognitive decline in hypertensive rats
N Szarka, L Toth, A Czigler, Z Kellermayer… - International Journal of …, 2019 - mdpi.com
… of blood … blood pressure. Therefore, future studies should test whether treated hypertension
exacerbates the effect of mild traumatic brain injury on BBB disruption, neuroinflammation …
exacerbates the effect of mild traumatic brain injury on BBB disruption, neuroinflammation …
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