Regenerative medicine for the treatment of spinal cord injury: more than just promises?

AP Pêgo, S Kubinova, D Cizkova… - Journal of Cellular …, 2012 - Wiley Online Library
… This review highlights some of the most promising clinical approaches to promoting spinal
cord regeneration that are under investigation at present, including ones already in clinical …

[HTML][HTML] Targeting mitochondrial function for the treatment of acute spinal cord injury

ML McEwen, PG Sullivan, AG Rabchevsky… - …, 2011 - Elsevier
… toward approaches that target entire organelles. In addition, a single treatment approach
may … be necessary to use a combination approach, such as NIM811 and ALC. Using such an …

[HTML][HTML] Clinical trials in traumatic spinal cord injury

J Donovan, S Kirshblum - Neurotherapeutics, 2018 - Elsevier
approaches to reduce secondary injury and also overcome barriers to neurorecovery. In the
future, it is likely that tailored treatments combining … approaches for adults with traumatic SCI. …

Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury

S Kabu, Y Gao, BK Kwon, V Labhasetwar - Journal of Controlled Release, 2015 - Elsevier
… Spinal cord injury (SCI) results in devastating neurological and … injury to the spinal cord
triggers a cascade of acute and chronic degenerative events, leading to further secondary injury. …

The International Spinal Research Trust's strategic approach to the development of treatments for the repair of spinal cord injury

GP Harper, PJ Banyard, PC Sharpe - Spinal cord, 1996 - nature.com
treat ment of spinal cord injury. Recently, ISRT has … spinal cord injury in this new study and
patients treated within 8 h were compared with those treated between 8 and 12 h after injury. …

Advances in regenerative therapies for spinal cord injury: a biomaterials approach

M Tsintou, K Dalamagkas… - Neural regeneration …, 2015 - journals.lww.com
… strategy for effective spinal cord injury repair. To this … approach of all the above. Here we
review the recent advances on regenerative/neural engineering therapies for spinal cord injury, …

Assessment and management of acute spinal cord injury: From point of injury to rehabilitation

LD Hachem, CS Ahuja, MG Fehlings - The journal of spinal cord …, 2017 - Taylor & Francis
Treatment begins in the field and a streamlined approach to management in the acute …
Overarching management goals at each stage following spinal cord injury. Each target must be …

Restoring function after spinal cord injury

D Becker, CL Sadowsky, JW McDonald - The neurologist, 2003 - journals.lww.com
… sexual dysfunction, and treatment demands a systematic clinical approach. Described are …
made biologic parenthood for men with spinal cord injuries a realistic option. Penile vibratory …

Spinal cord injury—what are the controversies?

CS Ahuja, GD Schroeder, AR Vaccaro… - Journal of orthopaedic …, 2017 - journals.lww.com
… Together, these biomarkers will allow us to better assess the efficacy of current and
upcoming treatment approaches, prognosticate with greater certainty, and tailor combinatorial …

Acute spinal cord injury: a systems approach

BA GREEN, FJ EISMONT - Central Nervous System Trauma, 1984 - liebertpub.com
cord injuriesinjury as automobile accidents. The majority of SCI victims suffer multisystem
trauma. The most common associated injury is long bone fractures, although visceral injuries