… of efficacy and safety of ferric carboxymaltose in patients with iron deficiency anaemia and impaired renal function (REPAIR-IDA): rationale and study design

LA Szczech, DB Bregman, RA Harrington… - Nephrology Dialysis …, 2010 - academic.oup.com
… Patients with iron deficiency anaemia (IDA) in the setting of non-dialysis-… from treatment
with intravenous (IV) iron. Ferric carboxymaltose (FCM) is a novel IV iron formulation designed to …

Rationale and design of the IRON-HF study: a randomized trial to assess the effects of iron supplementation in heart failure patients with anemia

L Beck-da-Silva, LE Rohde, AC Pereira-Barretto… - Journal of cardiac …, 2007 - Elsevier
… denominated as anemia of chronic disease (ACD), but the association with true ferropenic
anemia is common. Many studies have investigated the effects of treating anemia in HF …

Comparative safety of intravenous Ferumoxytol versus Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia: rationale and study design of a randomized …

NF Adkinson, WE Strauss, K Bernard… - Journal of Blood …, 2017 - Taylor & Francis
… Intravenous (IV) iron is often used to treat iron deficiency anemia in patients who are unable
to tolerate or are inadequately managed with oral iron. However, IV iron treatment has been …

Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal …

KA Barraclough, E Noble, D Leary, F Brown… - BMC nephrology, 2009 - Springer
Anemia develops early in the course of … design, potential for co-intervention and observer
biases, high drop-out rate (25% over 6 months) and failure to analyse on an intention to treat

Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

PS Myles, T Richards, A Klein, J Smith, EM Wood… - American Heart …, 2021 - Elsevier
… and preoperative intravenous (IV) iron therapy thus may improve anemia and … treatment of
anemia before cardiac surgery (ITACS) Trial to test the hypothesis that in patients with anemia

Rationale and design of oBservational clinical Research In chronic kidney disease patients with renal anemia: renal proGnosis in patients with Hyporesponsive …

H Kato, M Nangaku, H Hirakata, T Wada… - Clinical and …, 2018 - Springer
… Using darbepoetin alfa, an ESA commonly used to treat anemia in CKD patients, we aim to
gather a wide range of clinical information of ESA therapy to investigate the status of patients …

Rationale and design of Ferinject® Assessment in patients with IRon deficiency and chronic Heart Failure (FAIR‐HF) study: a randomized, placebo‐controlled study of …

SD Anker, JC Colet, G Filippatos… - European journal of …, 2009 - Wiley Online Library
… 24 months prior to start of treatment Anaemia due to reasons other than iron deficiency (eg
haemoglobinopathy) On optimal pharmacological treatment which includes a diuretic, a beta-…

Hydroxyurea therapy for children with sickle cell anemia in sub‐saharan africa: rationale and design of the REACH trial

PT McGann, L Tshilolo, B Santos… - Pediatric Blood & …, 2016 - Wiley Online Library
… The primary study endpoint will be severe hematological toxicities that occur during the
fixed-dose treatment phase. REACH has an adaptive statistical design that allows for careful …

Randomized placebo-controlled trial of ferric carboxymaltose in heart failure with iron deficiency: rationale and design

RJ Mentz, AP Ambrosy, JA Ezekowitz… - Circulation: Heart …, 2021 - Am Heart Assoc
… outcomes independent of baseline anemia. Several studies have shown … anemia. Similarly,
other international guidelines have recommended this treatment be considered for ID anemia

Rationale and design of the CONFIRM‐HF study: a double‐blind, randomized, placebo‐controlled study to assess the effects of intravenous ferric carboxymaltose on …

P Ponikowski, DJ Van Veldhuisen… - ESC heart …, 2014 - Wiley Online Library
… Ferric CarboxymaltOse evaluatioN on perFormance in patients with IRon deficiency in
coMbination with chronic Heart Failure (CONFIRM-HF) was designed to test a simplifieddosage …