New perspectives regarding β2adrenoceptor ligands in the treatment of asthma

JKL Walker, RB Penn, NA Hanania… - British journal of …, 2011 - Wiley Online Library
… interact with G protein-coupled receptors (GPCRs). Here we … can inactivate these
spontaneously active receptors; (iii) the … use of β 2 -adrenoceptor agonists in the treatment of …

[HTML][HTML] Past, present and future—β2-adrenoceptor agonists in asthma management

MR Sears, J Lötvall - Respiratory medicine, 2005 - Elsevier
β 2 -adrenoceptors ( β 2 -receptors) located in bronchial smooth muscle and have less
cardiotoxicity. Traditional β 2 -adrenoceptor agonists ( β 2 -… While valuable as reliever medication, …

β2-adrenoceptor function in asthma

Y Amrani, P Bradding - Advances in Immunology, 2017 - Elsevier
β2-adrenoceptor agonists are highly effective bronchodilator drugs used in the management
of pulmonary diseases such as asthmaβ 2 -agonists act on the β 2 -adrenoceptor which …

Long-acting beta 2-adrenoceptor agonists: a new perspective in the treatment of asthma

CG Lofdahl, KF Chung - European Respiratory Journal, 1991 - Eur Respiratory Soc
asthmatic airways, and concomitant treatment with an inhaled glucocorticoid is recommended,
particularly if regular use of inhaled ~ adrenoceptor … used in the treatment of asthma and …

β2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma

I Aziz, IP Hall, LC McFarlane, BJ Lipworth - Journal of Allergy and Clinical …, 1998 - Elsevier
β 2 -adrenoceptor downregulation and bronchodilator desensitization to albuterol occurred
at 36 hours after stopping regular treatment … mild-to-moderate stable asthma (mean [SD] age, …

Polymorphism of the beta2-adrenoceptor and the response to long-term beta2-agonist therapy in asthma

RJ Hancox, MR Sears, DR Taylor - European Respiratory …, 1998 - Eur Respiratory Soc
… find an association between β2adrenoceptor genotype and change in asthma control during
regular high dose inhaled β2-agonist therapy. We had hypothesized that the β2-receptor …

β-Adrenoceptor agonists and asthma—100 years of development

B Waldeck - European journal of pharmacology, 2002 - Elsevier
… While there may be reasons to continue using a well established β 2 -adrenoceptor
agonist in racemic form for the treatment of asthma, there is no excuse to use racemates in …

State-of-the-art beta-adrenoreceptor agonists for the treatment of asthma

WT Garzon-Siatoya, I Carrillo-Martin… - Expert opinion on …, 2022 - Taylor & Francis
… , particularly β 2 -adrenoreceptor agonists (β 2 -agonists) [… of β-adrenoceptor agonists in the
treatment of asthmatic patients. … support choosing levalbuterol over albuterol to treat asthma. …

The β-adrenoceptor

M Johnson - American journal of respiratory and critical care …, 1998 - atsjournals.org
β 2 -adrenoceptor agonist therapy (eg, tachycardia and physiologic tremor) in patients
with asthma… the importance of β 2 -adrenoceptor polymorphisms to the asthma phenotype. …

β-adrenoceptor responses of the airways: for better or worse?

KJ Broadley - European journal of pharmacology, 2006 - Elsevier
… having these various forms makes for a range of sensitivities to β 2 -adrenoceptor agonists
in the management of asthma and COPD. The effects of polymorphism do not appear to be …