Once‐daily inhaled budesonide for the treatment of asthma: clinical evidence and pharmacokinetic explanation

O Selroos, S Edsbäcker, C Hultquist - Journal of Asthma, 2004 - Taylor & Francis
… , and asthma symptom scores (p ≤ 0.001 each). In summary, infants and children with …
asthma can be effectively treated with once‐daily BIS. For children with more severe asthma

[HTML][HTML] Pharmacotherapy of asthma

MM Zdanowicz - American journal of pharmaceutical education, 2007 - ncbi.nlm.nih.gov
… may help explain the varying efficacy of anticholinergic drugs in … or modified to enhance their
pharmacokinetics and thus improve … efficacy of corticosteroids in treating asthma, long-term …

Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma

MG Matera, L Calzetta, B Rinaldi… - Expert opinion on drug …, 2017 - Taylor & Francis
… Following intravenous administration in a single ascending intravenous dose study (0.0003–3
mg/kg) in patients with mild atopic asthma, the pharmacokinetic activity was approximately …

Albuterol: an adrenergic agent for use in the treatment of asthma pharmacology, pharmacokinetics and clinical use

RC Ahrens, GD Smith - Pharmacotherapy: The Journal of …, 1984 - Wiley Online Library
… Perhaps the most likely explanation is that asthmatic patients developed a false sense of
security with the inhalers, and failed to seek appropriate medical care when they were critically …

A review of the pharmacokinetics of M3 muscarinic receptor antagonists used for the treatment of asthma

MG Matera, B Rinaldi, C Berardo… - Expert Opinion on …, 2020 - Taylor & Francis
… It is difficult to explain from the pharmacological point of view … of pharmacokinetic studies
has been performed in asthmatic … critical differences in the pharmacokinetic profile when the …

Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma

H Derendorf, R Nave, A Drollmann… - European …, 2006 - Eur Respiratory Soc
… -term treatment of asthma with ciclesonide at doses ranging 80–1,280 μg (ex-actuator) 82–88.
In summary, the pharmacokinetic and … exist in the pharmacokinetic and pharmacodynamic …

Stereoselective pharmacokinetics and pharmacodynamics of anti-asthma agents

M Vakily, R Mehvar, D Brocks - Annals of pharmacotherapy, 2002 - journals.sagepub.com
… Stereoselectivity in the pharmacokinetics of anti-asthma drugs may complicate the … of
the stereoselective pharmacokinetics and pharmacodynamics of chiral anti-asthma drugs …

[HTML][HTML] Monoclonal antibodies for severe asthma: Pharmacokinetic profiles

MG Matera, L Calzetta, P Rogliani, M Cazzola - Respiratory medicine, 2019 - Elsevier
… approved for the treatment of severe asthma. They have complex pharmacokinetic profiles.
… binding, as well as their glycosylation pattern, can influence the pharmacokinetics of mAbs. …

Pharmacokinetic considerations surrounding triple therapy for uncontrolled asthma

MG Matera, B Rinaldi, C Belardo… - Expert Opinion on …, 2023 - Taylor & Francis
pharmacokinetic characteristics of the three drug classes, the role of inhalers in influencing
their pharmacokinetic behavior, and the impact of severe asthma … The main explanation for …

Pharmacokinetic‐pharmacodynamic modeling of terbutaline bronchodilation in asthma

B Oosterhuis, MCP Braat, CM Roos… - Clinical …, 1986 - Wiley Online Library
… the feasibility of pharmacokinetic-pharmacodynamic … effect relationship with pharmacokinetic
dynamic modeling as … and the consequences for pharmacotherapy in bronchial asthma. …