Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis

PJ Little, A Chait, A Bobik - Pharmacology & therapeutics, 2011 - Elsevier
… anti-chemokine strategies to better treat atherosclerosis we need to consider the various
immune cells that contribute to development and progression of atherosclerosis, their cellular …

Lipaemia, inflammation and atherosclerosis: novel opportunities in the understanding and treatment of atherosclerosis

AJ van Oostrom, JPH van Wijk, MC Cabezas - Drugs, 2004 - Springer
Atherosclerosis and Inflammation Coronary heart disease is nowadays regarded as a low-grade
chronic inflammatory process.[48,49] Atherogenesis is initiated by endothelial injury …

Novel anti-inflammatory therapies for the treatment of atherosclerosis

R Khan, V Spagnoli, JC Tardif, PL L'Allier - Atherosclerosis, 2015 - Elsevier
inflammatory effects of serpin administration, colchicine and intravenous HDL-directed treatment
… for these novel anti-inflammatory treatments at both the experimental and clinical levels. …

Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies

A Zernecke, C Weber - Heart, 2012 - heart.bmj.com
processes and molecular mechanisms. Here we highlight the current view on atherosclerosis
and … Our understanding of the atherogenic process has been considerably refined by the …

Potential of anti-inflammatory agents for treatment of atherosclerosis

DA Chistiakov, AA Melnichenko, AV Grechko… - … and molecular pathology, 2018 - Elsevier
… Concomitant up-regulation of pro-inflammatory signalling pathways in vascular and blood
… key pro-inflammatory modulators as therapeutic targets for treatment of atherosclerosis. The …

Role of inflammatory cytokines in genesis and treatment of atherosclerosis

E Biros, JE Reznik, CS Moran - Trends in cardiovascular medicine, 2022 - Elsevier
… These foam cells play a decisive role in atherosclerosis … -γ), a primary inflammatory cytokine
in progressive atherosclerosis, … Here, we discuss the pro-atherosclerotic implication of this …

Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis

JA van Diepen, JFP Berbée, LM Havekes… - Atherosclerosis, 2013 - Elsevier
… Since anti-inflammatory drugs currently receive more and more attention with respect to …
treatment of atherosclerosis, we will summarize possible secondary effects of anti-inflammatory

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
… The first steps towards the development of anti-inflammatory treatments in atherosclerosis
were accomplished while studying patients with chronic inflammatory and autoimmune …

Atherosclerosis and inflammation: overview and updates

GR Geovanini, P Libby - Clinical science, 2018 - portlandpress.com
… that link inflammation and atherosclerosis and how we are at the threshold of translating
inflammation biology to improved patient care and more precise targeting of therapies. …

Anti-inflammatory strategies in atherosclerosis

H Bugger, A Zirlik - Hämostaseologie, 2021 - thieme-connect.com
… , which may aggravate atherosclerotic lesions, have lessened the enthusiasm for corticosteroid
therapy as a therapeutic option to mitigate inflammatory processes in atherosclerosis. …