… β-lactamase inhibitor combinations (BLBLICs) (3, 4) may still be used to treat infections with
ESBL-… Worldwide, numbers of infections caused by ESBL-producing Enterobacteriaceae are …

… can be confirmed as susceptible and the clinical scenario is appropriate, such as cystitis,
we suggest consideration of oral legacy antimicrobials to treat NDM-1-harboring infections. …

… β-lactamase inhibitor (avibactam, tazobactam, or clavulanic acid), inhibiting ESBLs if present,
might be useful to treat infections … -avibactam was proposed to treat infections caused MBL-…

… group of βlactamases is the metallo lactamases, or class B lactamases. These use a divalent
… these strains when treatment with these agents for Gram negative infections fails despite …

… , owing to the restricted empiric options available for treating infections with ESBL-producing …
Presently, CTX-M-β-lactamases include more than 220 different enzymes clustered into five …

… Although hyperproduction of β-lactamases or additional … However, the efficacy of BLBLI
for treating serious infections … infections (BSIs) caused by ESBL-EC who had been treated …

… infections for which few effective treatments remain increases, so does the contribution of
drug-hydrolyzing β-lactamase … This review highlights recent advances in β-lactamase inhibitors …

… -Lactams are a broad class of bactericidal agents that have been integral to the treatment
of infections … The bactericidal activity of β-lactams is mediated by inhibition of penicillin-binding …

… Carbepenems are the drugs of choice for the treatment of infections caused by ESBL
producing … Class B β-lactamases called as metallo beta lactamases (MBLs), act on penicillins, …

… the treatment of infections by extended-spectrum β-lactamase–… with difficult-to-treat
resistance (DTR-P. aeruginosa) [3]. … on the treatment of infections caused by AmpC β-lactamase–…