… Carbapenems are widely used for the management of bloodstream infections (BSIs) caused
by extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE). However, …

… antibiotics, resulting in difficult-to-treat infections. This review gives an introduction into the …
ESBL detection and the clinical relevance of infections caused by ESBL-producing organisms…

… Clinical experience with treating infections caused by NDM producers is limited, making it …
that infection with an NDM producer did not confer higher mortality as compared to infections …

… beta-lactams used in the treatment of severe infections in critical care. Clearly, information on
which beta-lactams … the carbapenems for the treatment of severe infections. Carbapenems …

… Given that carbapenems are necessary for treating serious infections, amikacin, cefepime, …
of infection, severity of infection, and treatment information in each episode of infection were …

… of the β-lactamase, has been widely used in the treatment of human infections. Although …
In structure E, the betalactamase remains covalently bound through an oxygen atom and an …

… spectrum serine β-lactamases. ANT-3310 inhibits both KPC and OXA carbapenemases and
is being partnered with meropenem for treatment of hospital-acquired infections due to Gram…

… To treat infections due to βlactamase-producing bacteria that were resistant to penicillin
and early cephalosporin derivatives, new generations of relatively enzyme-stable and broad-…

… β-lactamases, its clinical utility for the treatment of contemporary Acinetobacter infections is
… -stage development for the treatment of Acinectobacter infections, including those caused …

… for the treatment of orofacial odontogenic infections before … of β-lactams had occurred once
in the course of the infection … during the course of their infections, and no additional antibiotics …