… functions of the synovium, synovial fluid and synovial cells. The pathological … synovial cells
in OA are further summarized. More importantly, synovial cell-related techniques for OA treat…

… , subchondral bone alterations and synovitis. Current treatments are focused on symptomatic
relief but … Regenerative therapy for late OA phases would use stem cells and related cells. …

… synovial cells and macrophages. Cartilage breakdown products are also believed to result in
mononuclear cell infiltration and vascular hyperplasia in the synovial … of synovial interleukin-…

… osteoarthritis, as it orchestrates the cytokine cascade [29]. In vitro, IL-1 stimulates the chondrocytes
and synovial cells … of several molecules and ultimately to cell death via apoptotis and …

… , macrophages and fibroblasts lining the synovium produced detectable amounts of IL-…
synovial cells were infected with retroviral vector carrying IL-1Ra cDNA ex vivo. The infected cells …

… stem cells (MSCs) have been used widely for the treatment of … of exosomes secreted by
synovial membrane MSCs (SMMSC… stem cell-derived MSCs (iMSC-Exos) on the treatment of OA. …

… Osteoarthritis (OA) is one of the most debilitating diseases … Efforts to identify more tailored
treatment options led to the … benefit from a specific drug or cell-based therapy. Current clinical …

… We have summarized the cellular and molecular mechanisms of activated synovial
macrophages in the pathogenesis of OA-related pain. Future advances in the characterization of …

… a consensus of how best we can monitor and treat OA in a preclinical setting. Many experts
… ) generated by synovial cells is increased in serum in synovitis and this can be measured. …

… They found that synthesis of HA by human synovial cell lines was increased by the addition
of … from the start of treatment, was alteration in synovial membrane histopathology, assessed …