… A subgroup effect refers to a treatment effect in a specific proper subgroup. An interaction, or
… ¬ tial subgroup effect, refers to treatment effects that differ by subgroup. When a treatment is …

… Unfortunately, the fact that clinical effects that otherwise evaluated seem of trivial importance
often have large ORs might be one possible reason for the continued popularity and wide …

Importance In patients with severe community-acquired pneumonia, treatment failure is
associated with excessive inflammatory response and worse outcomes. Corticosteroids may …

… of the moderately hypertensive patients in the overview. Such a judgment is typically made
by comparing the patient's clinical history with the characteristics of the study patients, as …

… treatment was used alone or as add-on therapy. We were interested in both antidepressant
treatment effects … Because we were interested in the effect of anti-inflammatory treatment on …

… patients who did not reach clinical … clinical trial was to evaluate the efficacy and adverse
effects of convalescent plasma added to standard treatment, compared with standard treatment …

… To correct for possible differences between the two treatment groups in the number of
patients who developed little or no joint damage, we also analyzed data only from patients who …

… Although the study was not designed to assess sub-populations, we recorded no significant
effects of previous methotrexate treatment on clinical efficacy and radiographic endpoints. …

… Due to the paucity of information available on COVID-19 at the beginning of the trial for
estimation of event rates and treatment effects, we used a bayesian framework to guide serial …

… This article reports that remdesivir treatment for patients with moderate COVID-19 provides
some benefit, but the "difference was of uncertain clinical importance" [1]. Those conclusions …