… production by monocytes. In addition, we present unique profiles of monocytes/macrophages
contributing to identification of new biomarkers of disease activity or predicting treatment …

… The final factor in support of targeting monocytes/macrophages for treatment of RA is the …
transduction pathways that underlie different macrophage effector functions, in conjunction with …

… bone erosion in arthritis. Their plasticity is … monocytes/macrophages and treat experimental
arthritis, as well as potential consequences of anti-TNF biotherapy on monocyte/macrophage …

… -replacement rate, and that the rapid decrease in synovial macrophage numbers
observed after anti-TNF treatment (23) cannot be explained by an immediate effect on …

… Monocytes and macrophages lie at the core of inflammation … several cytokines also affect
the monocytes/macrophage axis [29]. … ) therapy [32]. In animal models of RA, depletion of total …

… consistent evidence that circulating monocytes contribute to the macrophage in the synovium
in … of M1 inflammatory macrophages using an antihuman DR5 (TRA-8) therapy in Cre LysM …

… by monocytes subsets and chemotaxis of circulating monocytes into RA synovium. Additionally,
we review monocytes as the circulating precursors of macrophages … to treatment by anti-…

… Rehder & EH Wilson (Family Menispermaceae), has been utilized to clinically treat
rheumatic and arthritic diseases for over 1,000 years by ancient Chinese physicians (22, 23). …

… Potential and established approaches for modulation of monocyte/macrophage (Mφ)
functions in rheumatoid arthritis. COX-2, cyclooxygenase-2; EC, endothelial cells; FB, fibroblasts; …

… of monocytes-macrophages to the synovium, which correlates with the down-regulation of
… Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor …