… This article reviews the role of CSCs, as they are currently understood, with a particular
focus on the role of CSCs in tumor growth, recurrence, metastasis, and treatment resistance. …

… Consequently, targeting CSCs to prevent tumor growth or regrowth might … tumor growth
and recurrence, in association with the development of resistance to common cancer treatments. …

… In colorectal cancer, CAFs-derived conditioned medium and … tumor growth of CSCs upon
treatment with 5-fluorouracil or oxaliplatin [107]. Chemotherapy-treated CAFs maintain cancer-…

… tumors promote cancer development … tumor progression and drug resistance [117]. Secreted
molecules such as exosome vesicles and microvesicles are occasionally modifiers of tumor …

… may be involved in the reduced responsiveness to the treatments. The current review
focuses on the role of stromal cells in tumor growth and in refractoriness to anti-VEGF treatment. …

… Throughout this review we will use the term CSC for practical purposes and we will discuss
their role in tumor growth and in drug resistance. TUMOR “DARWINISM” VERSUS CANCER …

… /nuclear localization with progression and prognosis of many tumor types, here the focus
is on experimental evidence for a causative role of YAP/TAZ in tumor growth and metastasis. …

… -anabolic” functions of Gln metabolism in regulating cell survival, oxidative stress resistance,
… findings and discuss their relevance to tumor biology and the potential for cancer therapy. …

… In this paper we investigated the role that fibroblasts play in tumor growth, organization
and treatment resistance. Using a combined experimental and theoretical approach, we …

… Stiffness along with tumor growth-induced solid stress and increased interstitial fluid pressure
contribute to tumor progression and therapy resistance. Second, the role of immune cells, …