Association between regimen composition and treatment response in patients with multidrug-resistant tuberculosis: a prospective cohort study

CM Yuen, EV Kurbatova, T Tupasi, JC Caoili… - PLoS …, 2015 - journals.plos.org
… was to gain insight into how regimen design affects treatment response by analyzing the …
To gain insight into how regimen design affects treatment response, we analyzed treatment

Time to culture conversion and regimen composition in multidrug-resistant tuberculosis treatment

DB Tierney, MF Franke, MC Becerra, FA Alcántara Virú… - PloS one, 2014 - journals.plos.org
regimen composition can be a chief source of such variability in early treatment response, …
may have been due to the composition of the background regimen. The implication of such a …

Association between changes in body composition and neoadjuvant treatment for pancreatic cancer

M Sandini, M Patiňo, CR Ferrone… - JAMA …, 2018 - jamanetwork.com
… Because NT is becoming the standard of care for patients with BRPC … composition and
clinical response. In this context, it may be proposed that screening changes in body composition

Development of new tuberculosis drugs: translation to regimen composition for drug-sensitive and multidrug-resistant tuberculosis

JP Ernest, N Strydom, Q Wang, N Zhang… - Annual review of …, 2021 - annualreviews.org
… 6-month regimen produces cure rates of over 95% (2–4). However, in practice, this complex
regimen often fails to meet these cure rates due to the lengthy duration of therapy, excessive …

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia

T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors… - Cancer discovery, 2013 - AACR
patients with partial or transitional clinical responses had a profound effect on the clonal
composition … The patient achieved complete remission under this drug regimen, but relapsed 5 …

Relevance of tumor-infiltrating immune cell composition and functionality for disease outcome in breast cancer

RD Bense, C Sotiriou… - Journal of the …, 2017 - academic.oup.com
… all patients benefit from standard treatment regimens (1,2), resulting in undertreatment or
overtreatment in many women. Predicting treatment response is … For the treatment regimen, we …

Increased regimen durability in the era of once-daily fixed-dose combination antiretroviral therapy

JH Willig, S Abroms, AO Westfall, J Routman… - Aids, 2008 - journals.lww.com
… Next, we evaluated the roles of dosing complexity and antiretroviral composition of regimens
as they relate to initial ART regimen durability using Kaplan–Meier plots and the log rank …

Raltegravir versus efavirenz regimens in treatment-naive HIV-1–infected patients: 96-week efficacy, durability, subgroup, safety, and metabolic analyses

JL Lennox, E DeJesus, DS Berger… - JAIDS Journal of …, 2010 - journals.lww.com
regimens had modest effects on serum lipids and glucose levels and on body fat composition
HIV jeopardizes the response to standard first-line regimens in certain treatment-naive …

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

SD Ahuja, D Ashkin, M Avendano, R Banerjee… - 2012 - journals.plos.org
treatment outcomes of microbiologically confirmed MDR-TB. Study authors were contacted
to solicit individual patient data including clinical characteristics, treatment … odds of treatment

[HTML][HTML] Designing drug regimens for special intensive care unit populations

BL Erstad - World Journal of Critical Care Medicine, 2015 - ncbi.nlm.nih.gov
composition that require special consideration when designing drug regimens: obese patients,
patients … limbs, pregnant patients, and patients undergoing ECMO or plasma exchange. …