Erlotinib in previously treated non–small-cell lung cancer

FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
Background We conducted a randomized, placebo-controlled, double-blind trial to determine
whether the epidermal growth factor receptor inhibitor erlotinib prolongs survival in non–…

Erlotinib: a new therapeutic approach for non-small cell lung cancer

P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
cure in up to 16% of patients with stage III lung cancer [6]. Despite modest improvement in
survival and symptom relief provided by systemic therapy, … rash in erlotinib-treated lung cancer

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… Symptom improvement in lung cancer patients treated with erlotinib: quality of life
analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. …

Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians

Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
Erlotinib and gefitinib, two small molecular agents that target the tyrosine kinase domain of
the EGFR, were approved in many countries for the treatmenterlotinib, as first-line treatment

[HTML][HTML] Erlotinib in advanced non-small cell lung cancer: efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study

M Reck, N van Zandwijk, C Gridelli, Z Baliko… - Journal of Thoracic …, 2010 - Elsevier
Erlotinib is a small molecule inhibitor of epidermal growth … with previously treated advanced
non-small cell lung cancer. Here, … trial of erlotinib (Tarceva Lung Cancer Survival Treatment). …

Determinants of tumor response and survival with erlotinib in patients with non—small-cell lung cancer

R Pérez-Soler, A Chachoua, LA Hammond… - Journal of clinical …, 2004 - ascopubs.org
erlotinib in patients with HER1/EGFR-expressing non–small-cell lung cancer previously treated
… The current study was planned to estimate the objective tumor response rate of erlotinib

Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
… -cell lung cancer who received erlotinib after other treatments had failed. Women, Asians,
patients with adenocarcinoma, and patients who had never smoked were more likely than …

Erlotinib in cancer treatment

MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… The EGFR is frequently expressed in a variety of epithelial tumors; non-small-cell lung
cancer (NSCLC) is among the epithelial cancers that are characterized by a generally high …

Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study

G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
… Purpose: Erlotinib has proven activity in pretreated patients with advanced non–small cell
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …

The role of erlotinib (Tarceva, OSI 774) in the treatment of non-small cell lung cancer

R Perez-Soler - Clinical cancer research, 2004 - AACR
Erlotinib (Tarceva) is a specific epidermal growth factor … Gefitinib (Iressa) shares with
erlotinib both a common chemical … as a third-line therapy for non-small cell lung cancer (NSCLC) …