Real-World Patterns of EGFR Testing and Treatment with Erlotinib for Non-Small Cell Lung Cancer in the United States

L Enewold, A Thomas - PloS one, 2016 - journals.plos.org
… EGFR mutation testing and erlotinib treatment among a population-… and/or receipt of erlotinib
were associated with survival. In … Cancer Institute (NCI) Patterns of Care (POC) lung cancer

[PDF][PDF] Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer

LV Sequist, J Von Pawel, EG Garmey, WL Akerley… - J Clin Oncol, 2011 - academia.edu
… in treatment, non–smallcell lung cancer (NSCLC) remains the leading global cause of cancer-…
, with a median survival of 10 to 12 months with aggressive therapy.Therefore, improving …

[HTML][HTML] A phase I study of erlotinib and hydroxychloroquine in advanced non–small-cell lung cancer

SB Goldberg, JG Supko, JW Neal, A Muzikansky… - Journal of Thoracic …, 2012 - Elsevier
cells treated with erlotinib or cisplatin, breast cancer cells treated with a HER2 TKI, and
melanoma cells treated … a beneficial adjunct to therapy in a broad range of clinical applications. …

Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer

Y Togashi, K Masago, S Masuda, T Mizuno… - Cancer chemotherapy …, 2012 - Springer
… during EGFR-TKI treatment (250 mg daily gefitinib or 150 mg daily erlotinib) between April
… Two of the 15 patients received gefitinib and erlotinib treatment; therefore, we analyzed 17 …

Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non–small-cell lung cancer: a phase III trial

GV Scagliotti, M Krzakowski, A Szczesna… - Journal of clinical …, 2012 - ascopubs.org
… Sunitinib plus erlotinib may enhance antitumor activity compared with either agent alone …
cell lung cancer (NSCLC), based on the importance of the signaling pathways involved in tumor

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… We identified two phase 2 trials that assessed the activity of erlotinib plus bevacizumab
as first-line treatment for EGFR-positive NSCLC: BELIEF and JO25567. The BELIEF study …

Erlotinib in the treatment of non-small cell lung cancer

ER Brown, FA Shepherd - Expert review of anticancer therapy, 2005 - Taylor & Francis
… in the treatment of patients with non-small cell lung cancer. A … This drug profile focuses on
the development of erlotinib, an … Results of clinical trials are reviewed, two trials of erlotinib in …

Antitumor activity of erlotinib (OSI-774, Tarceva) alone or in combination in human non-small cell lung cancer tumor xenograft models

B Higgins, K Kolinsky, M Smith, G Beck… - Anti-cancer …, 2004 - journals.lww.com
… kinase inhibitor erlotinib in athymic nude mice bearing non-small cell lung cancer (NSCLC) …
At the end of this study (day 47 post-tumor implantation, treatment day 19), erlotinib 100 mg/…

Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer

JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
Erlotinib is indicated for the treatment of patients with locally advanced or metastatic non-small
cell lung cancer (… for treatment of locally advanced, inoperable, or metastatic pancreatic …

[HTML][HTML] Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line …

B Coudert, T Ciuleanu, K Park, YL Wu, G Giaccone… - Annals of oncology, 2012 - Elsevier
… ) erlotinib is an established option for second-line treatment of patients with advanced NSCLC
[1., 2., 3.]. Treatment with erlotinib … that survival outcomes with erlotinib are similar to those …