The Current Situation: Erlotinib (Tarceva®) and Gefitinib (Iressa®) in Non-Small Cell Lung Cancer

RL Comis - The oncologist, 2005 - academic.oup.com
… therefore necessitate treatment with an erlotinib dose greater … on the erlotinib BR.21 data,
(e) the vast majority of lung cancer … from erlotinib-based interventions for advanced lung cancer

Gastric acid suppression is associated with decreased erlotinib efficacy in non–small-cell lung cancer

MP Chu, S Ghosh, CR Chambers, N Basappa… - Clinical lung cancer, 2015 - Elsevier
… Despite treatment advances, lung cancer remains the leading cause of cancer-related …
Cytotoxic chemotherapy has been the backbone of treating advanced non–small-cell lung cancer (…

Phase II trial of erlotinib plus concurrent whole-brain radiation therapy for patients with brain metastases from non–small-cell lung cancer

JW Welsh, R Komaki, A Amini, MF Munsell… - Journal of Clinical …, 2013 - ascopubs.org
… (first-line therapy) for patients with a new diagnosis of EGFR-mutated lung cancer. This …
In conclusion, this trial of concurrent erlotinib and radiation therapy for the initial treatment of …

[HTML][HTML] The concentration of erlotinib in the cerebrospinal fluid of patients with brain metastasis from non‑small‑cell lung cancer

Y Deng, W Feng, J Wu, Z Chen… - Molecular and …, 2014 - build.spandidos-publications.com
… In the future, it is recommended that the two methods are combined to treat non-small-cell
lung cancer patients with brain metastases. However, the optimal combination of the two types …

[HTML][HTML] The autophagy inhibitor chloroquine overcomes the innate resistance of wild-type EGFR non-small-cell lung cancer cells to erlotinib

Y Zou, YH Ling, J Sironi, EL Schwartz… - Journal of Thoracic …, 2013 - Elsevier
… implicated in cell proliferation and survival. , 2 Erlotinib is currently approved for the treatment
of chemorefractory non–small-cell lung cancer (NSCLC) and maintenance therapy after …

Influence of the acidic beverage cola on the absorption of erlotinib in patients with non–small-cell lung cancer

RWF van Leeuwen, R Peric… - Journal of Clinical …, 2016 - ascopubs.org
… Eligibility criteria were age 18 years and older, histology or cytology confirmed diagnosis
of lung cancer for which treatment with erlotinib monotherapy was indicated, use of erlotinib

[HTML][HTML] Erlotinib resistance in lung cancer: current progress and future perspectives

J Tang, R Salama, SM Gadgeel, FH Sarkar… - Frontiers in …, 2013 - frontiersin.org
… The phase I study explored the treatment of lung cancer cells with a combination of
erlotinib and permetrexed, which was well-tolerated and fairly successful in antitumor efficacy (…

Erlotinib in previously treated non-small-cell lung cancer

U Smrdel, V Kovač - Radiology and Oncology, 2006 - radioloncol.com
… nonsmall-cell lung cancer who receive erlotinib, the presence of … in the study treatment with
erlotinib through Tarceva EAP (… like to present a case of our first patient treated with erlotinib. …

Early Prediction of Nonprogression in Advanced Non–Small-Cell Lung Cancer Treated With Erlotinib By Using [18F]Fluorodeoxyglucose and [18F]Fluorothymidine …

T Zander, M Scheffler, L Nogova, C Kobe… - Journal of Clinical …, 2011 - ascopubs.org
… of erlotinib treatment were compared with nonprogression measured by computed
tomography after 6 weeks of treatment, progression-free survival (PFS), and overall survival (OS). …

Risk of interstitial lung disease with gefitinib and erlotinib in advanced non-small cell lung cancer: a systematic review and meta-analysis of clinical trials

L Shi, J Tang, L Tong, Z Liu - Lung Cancer, 2014 - Elsevier
… Reported incidence of ILD events in patients treated with gefitinib or erlotinib varied
substantially among trials. In a phase II study by Niho et al. in patients with NSCLC, four (10.0%) of …