Triazine dendrimers as drug delivery systems: From synthesis to therapy
J Lim, EE Simanek - Advanced drug delivery reviews, 2012 - Elsevier
… Triazine dendrimers have been used to deliver genes as … The delivery of siRNA with the
flexible G2 triazine dendrimers … flexible dendrimers were employed for further study in siRNA …
flexible G2 triazine dendrimers … flexible dendrimers were employed for further study in siRNA …
Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems
… suitable siRNA delivery systems based on flexible generation 2–4 triazine dendrimers by …
The siRNA binding properties of the dendrimers and PEI 25 kDa were simulated, binding …
The siRNA binding properties of the dendrimers and PEI 25 kDa were simulated, binding …
[HTML][HTML] Dendrimers for siRNA delivery
S Biswas, VP Torchilin - Pharmaceuticals, 2013 - mdpi.com
… effective gene delivery vector delivered significant amount of siRNA [102,104]. A … triazine
dendrimer for siRNA delivery. In comparison with PEI, 25 KDa, flexible G2-4 triazine dendrimers …
dendrimer for siRNA delivery. In comparison with PEI, 25 KDa, flexible G2-4 triazine dendrimers …
Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity
OM Merkel, MA Mintzer, D Librizzi… - Molecular …, 2010 - ACS Publications
… (28) In continuation we aim to elucidate structure−activity relationships regarding the impact
of peripheral and core functionality of triazine dendrimers on complex formation with siRNA …
of peripheral and core functionality of triazine dendrimers on complex formation with siRNA …
Dendrimers as non-viral vectors for siRNA delivery
… current status of dendrimers as siRNA delivery vectors, focusing on the different … of various
dendrimer vectors investigated for their siRNA delivery capacity. … Recently, a series of triazine …
dendrimer vectors investigated for their siRNA delivery capacity. … Recently, a series of triazine …
Triazine dendrimers for DNA and siRNA delivery: Progress, challenges, and opportunities
MA Mintzer, OM Merkel, T Kissel… - Dendrimer‐Based Drug …, 2012 - Wiley Online Library
… our triazine dendrimers as vectors for DNA and siRNA transfection, we looked to other
groups to determine what structural variations they had found most suitable for gene delivery in …
groups to determine what structural variations they had found most suitable for gene delivery in …
Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity
OM Merkel, MA Mintzer, J Sitterberg… - Bioconjugate …, 2009 - ACS Publications
… The potential of triazine dendrimers as gene delivery systems … These dendrimers may be
attractive candidates, as they can be … In addition, triazine dendrimers show low toxicity, both in …
attractive candidates, as they can be … In addition, triazine dendrimers show low toxicity, both in …
[PDF][PDF] MOLECULAR MODELING AND IN VIVO IMAGING CAN IDENTIFY SUCCESSFUL HYPERFLEXIBLE TRIAZINE DENDRIMER-BASED SIRNA DELIVERY …
… suitable siRNA delivery systems based on hyperflexible generation 2-4 triazine dendrimers
by … The siRNA binding properties of the dendrimers in comparison to PEI 25 kDa were …
by … The siRNA binding properties of the dendrimers in comparison to PEI 25 kDa were …
[HTML][HTML] Two decades of triazine dendrimers
EE Simanek - Molecules, 2021 - mdpi.com
… We concluded that triazine dendrimers offer a promising platform for drug delivery with a
high degree of control that can be exercised over composition. However, targeting that relied …
high degree of control that can be exercised over composition. However, targeting that relied …
Dendrimers as carriers for siRNA delivery and gene silencing: a review
J Wu, W Huang, Z He - The Scientific World Journal, 2013 - Wiley Online Library
… delivery systems. In this review, the development of dendrimer-based siRNA delivery …
2011, Merkel et al. tried to develop siRNA delivery carriers based on flexible G2–G4 triazine …
2011, Merkel et al. tried to develop siRNA delivery carriers based on flexible G2–G4 triazine …
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