Pretreatment with resveratrol ameliorate trigeminal neuralgia by suppressing matrix metalloproteinase-9/2 in trigeminal ganglion

Y Yin, R Guo, Y Shao, M Ge, C Miao, L Cao… - International …, 2019 - Elsevier
… activity induced by CCI were suppressed by resveratrol. Moreover, we believed that the …
pretreatment with resveratrol could be an effective approach to alleviate trigeminal neuralgia

Resveratrol as a potential therapeutic molecule against neuropathy: A new narrative

I Ahmad, R Rajagopalan, A Dey, M Hoda - … , Supplements, and Herbal …, 2023 - Elsevier
… of resveratrol in controlling neuropathic progression in two broad mechanisms. Resveratrol
may … Rat model Neuropathic pain (trigeminal neuralgia) Pretreatment of RSV alleviates …

[HTML][HTML] Modulatory mechanism of nociceptive neuronal activity by dietary constituent resveratrol

M Takeda, S Takehana, K Sekiguchi, Y Kubota… - International Journal of …, 2016 - mdpi.com
pretreatment of rats completely blocked the analgesic effect of … resveratrol could effectively
reduce clinical pain, including postoperative pain [65,66]. In patients with trigeminal neuralgia, …

Puerarin attenuates complete Freund's adjuvant-induced trigeminal neuralgia and inflammation in a mouse model via Sirt1-mediated TGF-β1/smad3 inhibition

K Du, W Wu, X Feng, J Ke, H Xie… - Journal of Pain …, 2021 - Taylor & Francis
… The aim of the present study was to determine the role of puerarin (Pue) in complete
Freund’s adjuvant (CFA)-induced trigeminal neuralgia (TN) and the effects of this compound on …

Deciphering resveratrol's role in modulating pathological pain: From molecular mechanisms to clinical relevance

B Wang, HM Jiang, LM Qi, X Li, Q Huang… - Phytotherapy …, 2024 - Wiley Online Library
… Furthermore, resveratrol pretreatment … , resveratrol could potentially alleviate trigeminal
neuralgia by diminishing the production of pro-inflammatory cytokines in the spinal trigeminal

[HTML][HTML] Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools

X Pan, J Chen, W Wang, L Chen, L Wang, Q Ma… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… were detected when pretreatment with ryanodine 30 min before resveratrol was given…
resveratrol's effect on p-CaMKII, ie significantly decreased p-CaMKII expression when pretreatment

[HTML][HTML] Recent update on trigeminal neuralgia

J Islam, KC Elina, YS Park - Journal of the Korean Society of …, 2022 - e-neurofunction.org
… choice due to its acceptable effectiveness even in pretreated and MS-related patients [36]. …
) in the glia of the spinal trigeminal nucleus (secondary TN) by resveratrol is useful in the …

Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms …

CA Miguel, MV Noya-Riobó, GL Mazzone… - Neurochemistry …, 2021 - Elsevier
… Rats received 20 or 40 mg/kg of resveratrol via ip injection 7 days prior to HIE induction.
Pretreatment with resveratrol reduced cerebral edema, infarct area, lipid peroxidation and …

[HTML][HTML] Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

Y Wang, Y Shi, Y Huang, W Liu, G Cai, S Huang… - Journal of …, 2020 - Springer
Resveratrol has shown neuroprotection by inhibiting inflammatory response in NeuP. … In
this study, we explored whether resveratrol could ameliorate neuroinflammation and produce …

[HTML][HTML] Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R

Y Cui, Y Li, J Ning, Y Mi, X Wang… - Molecular …, 2020 - spandidos-publications.com
… In addition, the analgesic effect of RES on trigeminal neuralgia involves suppression of
glial activation (15). It has been reported that RES alone or in combination with insulin or 4-…