Trypanosoma cruzi is an obligate intracellular parasite that infects phagocytic and non-phagocytic
mammalian cells by a complex process that appears to involve several discrete steps. …

… cruzi infection. In this review, the authors critically analyze the molecular and cellular
basis of early T. cruzi infection and discuss the future directions in this area. The candidate …

… experimental conditions used in the analyzed studies. While Trypanosoma cruzi preferentially
infects stromal cells in vivo, most of the assays employ epithelial cell lines. Furthermore, …

The paper reviews basic aspects of the biology of Trypanosoma cruzi emphasizing the following
topics: (a) developmental stages of the life cycle in the vertebrate and invertebrate hosts …

… Analyses of the cell surface of the T. cruzi epimastigotes have discovered differences in
the carbohydrate, protein, and lipid composition in comparison with trypomastigotes, so that …

… cell body morphologies, as well as nuclear architecture and kDNA arrangement. As a result
of this original and meticulous morphological analysis … biochemical and molecular analyses. …

… Digging deeper into this diversity, recent advances in individual cell analysis revealed the
importance of considering cellular populations as a complex mosaic of cells where cell to cell …

… To evaluate the effect of EVs over the cell cycle, cell cycle analyses using flow cytometry
and Western blotting of the phosphorylated and non-phosphorylated protein of Retinoblastoma …

… and parasites differentiate back into trypomastigotes that rupture the host cell to initiate a
new cellular infection cycle. For RNA-Seq analysis, total RNA was isolated from axenic T. …

… Comparative genomic analysis identified a potential role for an actin-myosin system in …
progress of studies related with the cell biology of Trypanosoma cruzi as well as other members of …