The genetics and genomics of Trypanosoma cruzi

MP Vazquez - 2007 - ri.conicet.gov.ar
cruzi was published in 2005, thus, providing a major tool to the understanding of several of
… This review highlights the fundamentals of the fascinating genetics and genomics of T. cruzi

[HTML][HTML] Genomics and functional genomics in Leishmania and Trypanosoma cruzi: statuses, challenges and perspectives

DC Bartholomeu, SMR Teixeira… - Memórias do Instituto …, 2021 - SciELO Brasil
… CRISPR/Cas9-induced disruption of paraflagellar rod protein 1 and 2 genes in
Trypanosoma cruzi reveals their role in flagellar attachment. mBio. 2015; 6(4): e01012. , …

A genomic scale map of genetic diversity in Trypanosoma cruzi

AA Ackermann, LG Panunzi, RO Cosentino… - BMC genomics, 2012 - Springer
… In this work we present an initial compilation of a genome-wide map of genetic diversity in
T. cruzi, and its functional analysis, focussed mostly on protein-coding regions of the genome. …

Trypanosoma cruzi Genome 15 Years Later: What Has Been Accomplished?

JL Ramirez - Tropical Medicine and Infectious Disease, 2020 - mdpi.com
genetic diseases was in the genome, LA researchers decided to launch a Trypanosoma cruzi
genome … piggyback on the successful Brazilian Xyllela fastidiosa genome project [13]. This …

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

W Wang, D Peng, RP Baptista, Y Li, JC Kissinger… - PLoS …, 2021 - journals.plos.org
… This genome flexibility also ensnares genes whose products are not targets of immune
responses, thus further driving the isolate-specific biological diversity that characterizes this …

A Genome-Wide Analysis of Genetic Diversity in Trypanosoma cruzi Intergenic Regions

LG Panunzi, F Agüero - PLoS neglected tropical diseases, 2014 - journals.plos.org
… , at least in part, by the genetic background of the parasite (infection by different … genetic
diversity in Trypanosoma cruzi were carried out on the protein-coding portions of the genome

Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications

A Herreros-Cabello, F Callejas-Hernández, N Gironès… - Genes, 2020 - mdpi.com
… by the parasite Trypanosoma cruzi affects millions of people. Although its first genome dates
… However, the new sequencing methods have improved genome annotation of some strains …

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

…, K Edwards, PT Englund, G Fazelina, T Feldblyum… - Science, 2005 - science.org
… Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that
the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …

Expanding an expanded genome: long-read sequencing of Trypanosoma cruzi

L Berná, M Rodriguez, ML Chiribao… - … genomics, 2018 - microbiologyresearch.org
… and annotated genomes of two Trypanosoma cruzi clones, … The complications associated
with this genome (assembly … of genes and other genomic features that are distinctive for T. …

The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi.

J Swindle, J Ajioka, H Eisen, B Sanwal… - The EMBO …, 1988 - embopress.org
We describe here the organization of the ubiquitin genes of the parasitic protozoan Trypanosoma
cruzi. T. cruzi contains greater than 100 ubiquitin coding sequences all of which are …