Epidemiologic and genetic aspects of spina bifida and other neural tube defects

KS Au, A Ashley‐Koch… - Developmental disabilities …, 2010 - Wiley Online Library
… incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000 births with
almost equal frequencies between two major categories: anencephaly and spina bifida (SB). …

Spina bifida and other neural tube defects

H Northrup, KA Volcik - Current problems in pediatrics, 2000 - Elsevier
… 2, 3 Meningomyelocele, also called spina bifida or spina bifida cystica, is … of the spinal
cord and meninges through a defect in the vertebral arch can occur anywhere along the spinal

Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects

VN Houk, GP Oakley, JD Erickson, J Mulinare… - 1992 - stacks.cdc.gov
tube defects (NTDs) spina bifida and anencephaly. In addition, an unknown number of fetuses
affected by these birth defects … of babies born with spina bifida grow to adulthood with, in …

Postnatal management and outcome for neural tube defects including spina bifida and encephalocoeles

DNP Thompson - … Diagnosis: Published in Affiliation With the …, 2009 - Wiley Online Library
… It must be emphasized that this review deals exclusively with ‘open’ neural tube defects.
This data cannot be extrapolated to the skin covered, or closed dysraphic states such as …

Spina bifida

LE Mitchell, NS Adzick, J Melchionne, PS Pasquariello… - The Lancet, 2004 - thelancet.com
… The mechanism underlying the association between neural tube defects and folate has not
been established. However, folate participates in two metabolic pathways that, if disrupted, …

Spina bifida

AJ Copp, NS Adzick, LS Chitty, JM Fletcher… - Nature reviews Disease …, 2015 - nature.com
… Schematic representation of several neural tube defects (NTDs). Spina bifida occulta is
found in up to 10% of people and usually occurs in the low spinal region. Closed …

Neural tube defects

NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
… brain and spinal cord results in anencephaly and open spina bifida (… ; spina bifida cystica)
or exposed directly to the amniotic fluid (myelocele). Babies born with open spina bifida

Children with spina bifida: key clinical issues

AD Sandler - Pediatric Clinics, 2010 - pediatric.theclinics.com
Spina bifida is the most common of the neural tube defects (NTDs), which include
myelomeningocele, encephalocele, and anencephaly. Spina bifida … The spinal cord is normal, and …

Use of folic acid for prevention of spina bifida and other neural tube defects--1983-1991

Centers for Disease Control … - MMWR. Morbidity and …, 1991 - pubmed.ncbi.nlm.nih.gov
tube defect have a 2%-3% risk for having another pregnancy resulting in an infant or fetus
with a neural tube defect (ie, … the recurrence of neural tube defects. This report summarizes the …

Clinical, genetic, and epidemiological factors in neural tube defects.

JG Hall, JM Friedman, BA Kenna, J Popkin… - American Journal of …, 1988 - ncbi.nlm.nih.gov
… We used the criteria of Toriello and Higgins (1985) to define a canalization-related defect
as spina bifida in which the highest extent of the lesion or of associated radiographically …