… potential combinations employing new drugs and optimized doses of existing drugs. Building
a wholly new regimen by assessing single drug substitutions (of a new drug for an old one) …

… the chemotherapy of established tuberculosis, which has proved remarkably useful in
assessing the value of the different drugs. The main problem in clinical assessment arises from the …

… Several Phase II clinical trials are in progress, in which rifampicin is replaced by high-dose
rifapentine, to assess its potential to shorten the treatment duration of drug-susceptible TB. …

… entered preliminary clinical trials.The clinical assessment of new anti-tuberculosis drugs is a
… adult patients with microbiologically proven pulmonary tuberculosis (TB).While preliminary …

… The phase of clinical testing of new anti-TB drugs is time-consuming, as the current “gold
standard” to assess efficacy of anti-TB regimens in phase III clinical trials is the relapse rate 2 …

… Here, we assess the evidence supporting currently utilized and … response in active and
latent tuberculosis. Biomarkers for … Clinical assessments include overall performance status, …

… multiple-drug combinations to assess their 14… clinical and clinical evaluation for the treatment
of TB. We are more used to read the common statement that no new anti-tuberculosis drugs …

… It is, therefore, important that clinicians are aware of its manifestations … of drug-resistant
tuberculosis but with careful assessment and treatment it appears that drug-resistant tuberculosis …

… use at higher doses or in new drug combinations (rifamycins, … TB drug arsenal, killing
Mycobacterium tuberculosis through … However, a recent assessment conducted by the TB Alliance …

… of clinical data to enhance the current ECG assessment was … They hypothesized that the
effects of multichannel drug block … In a clinical study led by Johannesen, four drugs were given …