Biomarkers for discrimination between latent tuberculosis infection and active tuberculosis disease

EJ Won, JH Choi, YN Cho, HM Jin, HJ Kee, YW Park… - Journal of Infection, 2017 - Elsevier
… of combinations of biomarkers to discriminate between Mtb-infected and uninfected groups
or between active TB and LTBI. Optimal combinations of biomarkers were investigated by …

Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis

M Jacobsen, D Repsilber, A Gutschmidt… - Journal of molecular …, 2007 - Springer
tuberculosis infection. As a first step to determine additional biomarkers, we compared gene
expression profiles of peripheral blood mononuclear cells from tuberculosis patients and M. …

Identification of plasma biomarkers for discrimination between tuberculosis infection/disease and pulmonary non tuberculosis disease

MP La Manna, V Orlando, P Li Donni, G Sireci… - PLoS …, 2018 - journals.plos.org
… were a feature of TB infection/disease or were … -TB pulmonary infections (n.20). As reported
in Table 2, 29 out of 30 analytes were increased both in sera of TB patients and in NON-TB

Potential biomarkers associated with discrimination between latent and active pulmonary tuberculosis

…, J Waruk, A Meyers, J Ochanda, TB Ball… - … of Tuberculosis and …, 2017 - ingentaconnect.com
biomarkers that are significantly different between active TB and LTBI and those that could
potentially discriminate between TB infection … to identify putative biomarkers of TB disease in …

Discriminating between latent and active tuberculosis with multiple biomarker responses

M Frahm, ND Goswami, K Owzar, E Hecker, A Mosher… - Tuberculosis, 2011 - Elsevier
biomarkers could a) be more sensitive for TB infection than a single immune marker, and b)
potentially distinguish individuals with active TB disease from persons with latent TB infection

A systematic review of biomarkers to detect active tuberculosis

E MacLean, T Broger, S Yerlikaya… - Nature …, 2019 - nature.com
… Most publications were excluded for not addressing the target condition of active TB detection.
For example, many publications reported biomarkers for latent TB infection detection or …

Tuberculosis biomarkers: from diagnosis to protection

D Goletti, E Petruccioli, SA Joosten… - Infectious disease …, 2016 - mdpi.com
… and neopterin might discriminate TB patients from subjects with other infectious and inflammatory
… Latent tuberculosis infection detection and active tuberculosis prevention in patients …

Cytokine biomarkers for the diagnosis of tuberculosis infection and disease in adults in a low prevalence setting

V Clifford, M Tebruegge, C Zufferey, S Germano… - Tuberculosis, 2019 - Elsevier
… candidate mycobacterial antigen-stimulated cytokine biomarkers can discriminate between
TB-uninfected and TB-infected adults, and additionally between LTBI and active TB disease. …

Identification of candidate host serum and saliva biomarkers for a better diagnosis of active and latent tuberculosis infection

O Estévez, L Anibarro, E Garet, Á Pallares, A Pena… - PLoS …, 2020 - journals.plos.org
biomarkers to discriminate between active TB patients (n = 28), latent … biomarker to
discriminate active and latent TB infection in saliva samples. On the other hand, for discrimination

Immunological biomarkers of tuberculosis

G Walzl, K Ronacher, W Hanekom, TJ Scriba… - Nature Reviews …, 2011 - nature.com
tuberculosis infection stages and their potential use in the fight against … with four other
transcripts, could discriminate between active disease and latent infection. Genes related to the …