… We recently studied proximal tubulederived lEVs (megalin+) in a mouse model of adenine-…
of tubular lEVs parallel to improvement in tubular injury in adenine-fed mice [30]. Thus tubular …

… /progenitors improve the recovery of acute kidney injury (AKI) mainly through the release of
paracrine mediators including the extracellular vesicles (EVs). Several studies have reported …

… In this report, we describe the use of renal cell extracellular vesicles (EV) to treat ischemic
renal injury in rats. We derived this work from prior experimentation that showed improved …

… extracellular vesicles (sEV) after AKI. In response to renal ischemia/reperfusion (I/R) injury,
endothelial proliferation of PTCs and tubular … the basolateral side of tubular cells. Meanwhile, …

… Among the recent therapeutic options, the use of extracellular vesicles (EVs) is considered
… injury generated by glycerol injection. uEVs accelerated renal recovery, stimulating tubular …

… MSCs are transiently recruited in the injured kidney and act by a paracrine … tubular epithelial
cells (PTECs) was also shown to be mediated through secretion of extracellular vesicles (…

… This study reported that the extracellular vesicles were taken up by proximal tubule … were
more effective than free extracellular vesicles at limiting tubular injury in the early stages of AKI …

… to tubular injury. microRNAs (miRNAs) in extracellular vesicles (EVs) can modulate distant
cells… We hypothesized that miRNAs in EVs derived from injured podocytes lead to tubular …

… Thus, injured tubular epithelial cells release EVs that can stimulate macrophage activation
and infiltration, amplifying inflammation [50]. Importantly, EVs derived from macrophages can …

… pivotal impact of their study on extracellular vesicle therapy. Acute kidney injury (AKI), the …
, which represents a novel direction for using extracellular vesicles (EVs) for AKI therapy (…