… tumor target cells We examined the role of the Fas pathway in NK-CMC against tumor cells
… Three cell lines were used, namely U937, CEM and Jurkat cells, and all three expressed sur…

… pathways such as the CD95 system may play a role in determining sensitivity or resistance
of tumor cells to … of CD95 in tumor cells by cytokines or cytotoxic drugs may be involved in …

… -arginine deiminase pathway (46). They are cytostatic and cytotoxic to tumor cells and
microorgan… deiminase, inhibits tumor cell lysis by activated macrophages and prevents the loss of …

… tumor cells could resist cytotoxicity due to anticancer agents. Apoptosis is not the only form
of … pathways in determining the sensitivity of hematopoietic tumor cells to cytotoxic agents. …

… The PI3K/Akt/GSK-3β/ROS/eIF2B pathway could regulate NK cell activity and sensitivity
of tumor cells to NK cells, which … Thus, GSK-3β is a promising target of anti-tumor therapy. …

… of the TNF-α pathway in docetaxel cytotoxicity and in the induction of docetaxel resistance,
we also showed in this study that selection of breast and ovarian tumor cells for resistance to …

… the cytotoxic mechanisms involved in autologous tumor cell lysis by the … the tumor cell line
was resistant to TNF-induced lysis. Resistance to TNF, frequently developed by several tumors …

… In this article, the two main pathways involved in CL-mediated tumor cell death, granule
exocytosis (perforin and granzymes) and death ligands, are briefly introduced, followed by a …

… cells. Thus our results provide compelling evidence for involvement of AR in deciding types
of tumor cell death upon cytotoxic … of AR in facilitating tumor cell death in the current study. …

… this prosurvival pathway induced by hypoxia and “push” hypoxic tumor cells into necrosis
by … in vivo, which we predict will show even greater cytotoxicity toward hypoxic tumor cells. …