The Warburg effect and mitochondrial stability in cancer cells
V Gogvadze, B Zhivotovsky, S Orrenius - Molecular aspects of medicine, 2010 - Elsevier
… Since most tumor cells demonstrate a remarkable resistance to drugs that kill non-malignant …
conditions, the Warburg effect, was found to be a characteristic of most cancer cells, and this …
conditions, the Warburg effect, was found to be a characteristic of most cancer cells, and this …
The Warburg effect: how does it benefit cancer cells?
MV Liberti, JW Locasale - Trends in biochemical sciences, 2016 - cell.com
… Warburg Effect remains unclear. Here, we analyze several proposed explanations for the
function of Warburg Effect… evidence indicates that tumor cells can communicate with cells in the …
function of Warburg Effect… evidence indicates that tumor cells can communicate with cells in the …
Warburg effect or reverse Warburg effect? A review of cancer metabolism
XD Xu, SX Shao, HP Jiang, YW Cao… - Oncology research and …, 2015 - karger.com
… to distinguish tumor cells from normal cells. Cancer … cells were indeed as high as those of
normal cells. This threw down the gauntlet to the Warburg effect as the example of cancer cell …
normal cells. This threw down the gauntlet to the Warburg effect as the example of cancer cell …
New aspects of the Warburg effect in cancer cell biology
SJ Bensinger, HR Christofk - Seminars in cell & developmental biology, 2012 - Elsevier
… Therefore, loss of p53 expression in tumor cells may facilitate the Warburg effect by
simultaneously increasing flux through glycolysis and decreasing oxidative phosphorylation. For a …
simultaneously increasing flux through glycolysis and decreasing oxidative phosphorylation. For a …
[HTML][HTML] Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect
X Chen, L Li, Y Guan, J Yang, Y Cheng - Acta Pharmacologica Sinica, 2016 - nature.com
… tumor cells die quickly, but with lactate acidosis, they convert glucose at a slower rate and
maintain cell proliferation by transitioning from the Warburg effect … “Reverse Warburg effect” or “…
maintain cell proliferation by transitioning from the Warburg effect … “Reverse Warburg effect” or “…
[HTML][HTML] Warburg effect (s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism
AM Otto - Cancer & metabolism, 2016 - Springer
… think about tumor metabolism. Particularly, in the field of cancer research, we are using the
term “Warburg effect” to denote a metabolic phenotype typical of many tumor cells, namely …
term “Warburg effect” to denote a metabolic phenotype typical of many tumor cells, namely …
Warburg effect and its role in tumourigenesis
… This review focuses on the contribution of the Warburg effect to tumourigenesis and
addresses signaling of aberrant tumourigenic metabolism regarding the microenvironment, …
addresses signaling of aberrant tumourigenic metabolism regarding the microenvironment, …
The warburg effect: why and how do cancer cells activate glycolysis in the presence of oxygen?
M López-Lázaro - Anti-Cancer Agents in Medicinal Chemistry …, 2008 - ingentaconnect.com
… that cancer cells and non-malignant proliferating cells can activate … or Warburg effect).
Accumulating evidence suggests that the persistent activation of aerobic glycolysis in tumor cells …
Accumulating evidence suggests that the persistent activation of aerobic glycolysis in tumor cells …
How the Warburg effect supports aggressiveness and drug resistance of cancer cells?
P Icard, S Shulman, D Farhat, JM Steyaert… - Drug Resistance …, 2018 - Elsevier
… We also show how this metabolic shift towards increased glycolytic functioning sustains
tumor cell … As discussed in the current review, the Warburg effect also promotes many tumor …
tumor cell … As discussed in the current review, the Warburg effect also promotes many tumor …
Understanding the Warburg effect: the metabolic requirements of cell proliferation
MG Vander Heiden, LC Cantley, CB Thompson - science, 2009 - science.org
… the signaling pathways that control cell growth have led researchers back to the seminal
work of Otto Warburg, who discovered in the 1920s that tumor cells generate their energy in an …
work of Otto Warburg, who discovered in the 1920s that tumor cells generate their energy in an …
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