Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
tumor cells abundantly release small vesicles known as extracellular vesicles (EVs) into the
extracellular … In this review, we aimed to discuss the tumor-derived exosome biology and the …

Basics and applications of tumor-derived extracellular vesicles

YL Tai, PY Chu, BH Lee, KC Chen, CY Yang… - Journal of biomedical …, 2019 - Springer
Extracellular vesicle (EV)-mediated intercellular communication acts as a critical culprit in
cancer development. The selective packaging of oncogenic molecules renders tumor-derived

Tumor-derived extracellular vesicles: The metastatic organotropism drivers

J Rezaie, M Ahmadi, R Ravanbakhsh, B Mojarad… - Life Sciences, 2022 - Elsevier
… of extracellular vesicles (EVs) in tumor metastasis. Tumor cells release EVs into the extracellular
… A growing body of evidence suggests that primary tumor derived EVs contribute to the …

[HTML][HTML] Tumor-derived extracellular vesicles: Potential tool for cancer diagnosis, prognosis, and therapy

T Saleem, A Sumrin, M Bilal, H Bashir… - Saudi Journal of …, 2022 - Elsevier
… With the discovery of the fact that tumor cells discharge huge quantities of EVs, new …
Tumor-derived extracellular vesicles (TD-EVs) can be distinguished from the normal cell-derived

Tumor-derived extracellular vesicles in breast cancer: From bench to bedside

HX Wang, O Gires - Cancer letters, 2019 - Elsevier
Tumor-derived extracellular vesicles (TEVs) released from various tumor cell types comprise
endosome-derived exosomes and microvesicles (MVs), which originate from plasma …

Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment

JW Clancy, C D'Souza-Schorey - Annual Review of Pathology …, 2023 - annualreviews.org
Tumor cells release extracellular vesicles (EVs) that can function as mediators of intercellular
communication in the tumor microenvironment. EVs contain a host of bioactive cargo, …

[HTML][HTML] Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

VR Minciacchi, S You, C Spinelli, S Morley… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Large oncosomes (LO) are atypically large (1-10μm diameter) cancer-derived extracellular
vesicles (EVs), originating from the shedding of membrane blebs and associated with …

Engineered tumor-derived extracellular vesicles: potentials in cancer immunotherapy

A Taghikhani, F Farzaneh, F Sharifzad… - Frontiers in …, 2020 - frontiersin.org
… Based on data that we described herein, we suggest that tumor derived extracellular vesicles
could be manipulated and provide cancer treatment. In this way, tumor-associated antigens…

Tumor-derived extracellular vesicles in cancer immunoediting and their potential as oncoimmunotherapeutics

M Najaflou, M Shahgolzari, AY Khosroushahi, S Fiering - Cancers, 2022 - mdpi.com
… M2 through macrophage polarization with exposure to tumor-derived factors and TEVs in the
TME and … functions for the tumor [26,27]. Cancer-derived extracellular vesicles increase M2 …

Molecular identification of tumor-derived extracellular vesicles using thermophoresis-mediated DNA computation

Y Li, J Deng, Z Han, C Liu, F Tian, R Xu… - Journal of the …, 2021 - ACS Publications
Molecular profiling of tumor-derived extracellular vesicles (tEVs) holds great promise for non-invasive
cancer diagnosis. However, sensitive and accurate identification of tEVs is …